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Table 2 Clinical characteristics: comparison of patients with and without asthma (n = 473)

From: Asthma in patients hospitalized with pandemic influenza A(H1N1)pdm09 virus infection–United States, 2009

Characteristic

Patients with asthma

Patients without asthma

P-Value*

 

No. (%) (n = 137)

No. (%) (n = 336)

 

Median days from onset to admission (range)

2 (0 – 20) (n = 136)

3 (0 – 21) (n = 332)

0.06

Admission within 2 days of illness onset

74/136 (54)

150/334 (45)

0.06

Median length of stay- days (range)

3 (0 – 47) (n = 136)

3 (0 – 77) (n = 332)

0.14

Clinical symptoms at admission

   

 Cough

118 (86)

284 (85)

0.45

 Fever

115 (84)

294 (88)

0.20

 Shortness of Breath

91 (66)

155 (46)

<0.01

 Wheezing

62 (45)

47 (14)

<0.01

 Fatigue/Weakness

47 (34)

125 (37)

0.71

 Myalgias

43 (31)

122 (36)

0.57

 Rhinorrhea

42 (31)

103 (31)

0.88

 Chills

38 (28)

120 (36)

0.23

 Sore Throat

33 (24)

96 (29)

0.25

 Vomiting

31 (23)

98 (29)

0.08

 Headache

31 (23)

99 (30)

0.17

 Diarrhea

18 (13)

75 (22)

0.03

Underlying medical condition

   

 Any condition excluding asthma

64 (47)

217 (50)

0.11

 Diabetes

24 (18)

51 (15)

0.18

 Chronic obstructive pulmonary disease

18 (13)

31 (9)

0.04

 Cardiovascular disease

16 (12)

52 (16)

0.55

 Immunosuppression

15 (11)

48 (14)

0.45

 Neuromuscular disorder

11 (8)

26 (8)

0.87

 Cognitive dysfunction

10 (7)

25 (7)

0.76

 Seizure disorder

7 (5)

25 (7)

0.21

 Chronic renal disease

3 (2)

38 (11)

<0.01

Pregnancy

8 (6)

38 (12)

0.11

Current smoker

23/121 (19)

58/303 (19)

0.56

Obese or morbidly obese

47/129 (36)

103/298 (35)

0.37

Positive sterile site culture

1/137 (1)

13/336 (4)

0.11

Pneumonia at admission

45/123 (37)

133/281 (47)

0.05

Seasonal flu vaccine

33/86 (38)

64/203 (32)

0.49

  1. * P-Values stratified by age-group.
  2. Body-Mass Index (BMI) was calculated for a subset of patients for whom height and weight were available to determine obesity (BMI 30–39.9 in adults ≥18 years or BMI percentile 95–100 in children 2 to 19 years old) and morbid obesity (BMI ≥40 in adults only); pregnant women were excluded from this calculation.