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Table 2 Specificity of the antigenic regions present in CRA and FRA sequences that were identified by the Spot-synthesis technique in comparison to similar sequences of those identified as antigenic for T. cruzi according to the Expasy data base ( http://www.uniprot.org/ )

From: Chagas disease-specific antigens: characterization of epitopes in CRA/FRA by synthetic peptide mapping and evaluation by ELISA-peptide assay

Acession number

Protein name

Organism

Identity

  (%)

CRA-1 (KQKAAEATK)

Q9NJH4

Antigen JL8

T. cruzi

100

Q4DV01

R27-2 protein, putative

T. cruzi

100

Q4DN44

Putative uncharacterized protein

T. cruzi

100

Q26947

R27-2 protein

T. cruzi

100

E7LGS7

Putative uncharacterized protein

T. cruzi

100

B9V414

Antigen

T. cruzi

100

CRA-2 (KQRAAEATK)

Q4DV01

R27-2 protein, putative

T. cruzi

100

Q4DN44

Putative uncharacterized protein

T. cruzi

100

Q26947

R27-2 protein

T. cruzi

100

E7LGS7

Putative uncharacterized protein

T. cruzi

100

B9V414

Antigen

T. cruzi

100

FRA-4 (ADRAFLDQPERVP)

Q04946

Cytoskeleton associated protein

T. cruzi

92

Q4CS87

Calpain cysteine peptidase, putative

T. cruzi

92

Q4CPQ6

Calpain cysteine peptidase, putative

T. cruzi

92

Q26898

Antigen DNA (tandem repeat sequence)

T. cruzi

92

E7LGE0

Calpain cysteine peptidase, putative

T. cruzi

92

A4HFX3

Putative calpain-like cysteine peptidase

L. braziliensis

90

E9AHC1

Putative cysteine peptidase

L. infantum

76