Table 1 Characteristics of TB patients and non-TB controls
From: The discovery and identification of a candidate proteomic biomarker of active tuberculosis
Training set | Testing set | Clinical set | Total | |
|---|---|---|---|---|
TB | ||||
Total number of patients | 120 | 60 | 142 | 322 |
Years range, age (media ± SD) | 18-65(43.5 ± 12.0) | 19-63 (44.4 ± 12.6) | 20-62 (46.1 ± 10.5) | 18-65 (44.7 ± 11.7) |
Sex (female: male) | 52:68 | 26:34 | 61:81 | 139:183 |
Abnormal chest radiograph | 120 (100%) | 60 (100%) | 142 (100%) | 322 (100%) |
Sputum culture-positive | 76 (63.3%) | 41 (68.3%) | 92 (64.8%) | 209 (65.0%) |
Sputum culture-negative | 44 (36.7%) | 19 (31.7%) | 50 (35.2%) | 113 (35.0%) |
Pathogens identified | 19 (15.8%) | 8 (13.3%) | 21 (14.8%) | 48 (14.9%) |
Histopathological changes of TB | 3 (2.5%) | 1 (1.7%) | 3 (2.1%) | 7 (2.1%) |
Comprehensive dianoisis and confirmed by anti-tuberculosis treatment response | 22 (18.3%) | 10 (16.7%) | 26 (18.3%) | 58 (18.0%) |
BCG vaccination | 52 (43.3%) | 27 (45.0%) | 55 (39%) | 134 (41.6%) |
HIV-negative | 120 (100%) | 60 (100%) | 142 (100%) | 322 (100%) |
Non-TB controls | ||||
Total number of control subjects | 120 | 91 | 211 | |
Healthy volunteers | 60 (50.0%) | 31 (34.1%) | 91 (43.1%) | |
Lung cancer | 20 (16.7%) | 20 (22.0%) | 40 (19.0%) | |
Pneumonia | 20 (16.7%) | 20 (22.0%) | 40 (19.0%) | |
Chronic obstructive pulmonary disease | 20 (16.7%) | 20 (22.0%) | 40 (19.0%) | |
Years range, age (media ± SD) | 20-65 (46.5 ± 13.9) | 19-64 (46.1 ± 14.4) | 19-65 (46.3 ± 14.1) | |
Sex (female: male) | 48:72 | 38:53 | 86:125 | |
BCG vaccination | 53 (44.2%) | 39 (42.9%) | 92 (43.6%) | |
HIV-negative | 120 (100%) | 91 (100%) | 211 (100%) | |
Total | 240 | 151 | 533 |