High incidence of septic shock caused by Streptococcus pneumoniae serotype 3 - a retrospective epidemiological study

Table 3 Prevalence of co-morbidities, associated mortality, incidence of septic shock, and ICU admission per co-morbidity

Type of co-morbidity^a	Number of patients (%)	28 day mortality (%)	Septic shock (%)	Admitted to the ICU (%)
Cardiovascular disease	136 (27%)	25 (18%)	18 (13%)	26 (19%)
Lung disease	125 (24%)	20 (16%)	20 (16%)	26 (21%)
Neurological disease	67 (13%)	12 (18%)	9 (13%)	10 (15%)
Diabetes mellitus	61 (12%)	10 (6%)	12 (20%)	12 (20%)
Solid cancer	50 (10%)	7 (14%)	5 (10%)	5 (10%)
Hematologic disease^b	48 (10%)	9 (19%)	4 (8%)	5 (10%)
Immunosuppression^c	55 (11%)	11 (20%)	8 (14%)	11 (20%)

^aOther reported co-morbidities were in descending order; renal disease (n=23), autoimmune disease (n=19), liver disease (n=17), splenectomy (n=4) and HIV (n=3).
^bHematologic disease includes hematological malignancies.
^cPharmacological immunosuppression was noted if the patient was treated with biological drugs, methotrexate or corticosteroids equivalent to ≥ 10 mg prednisolone.

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