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Table 1 Characteristics of patients with IPD by infecting serotype and statistical comparison in relation to infection with serotype 14

From: High incidence of septic shock caused by Streptococcus pneumoniae serotype 3 - a retrospective epidemiological study

  Septic shock 28 day mortality Admitted to the ICU Any co-morbidity Two or more co-morbidities per patient Median age
Serotype (no) Percent of all isolates No (%) OR (CI) No (%) OR (CI) No (%) OR (CI) No (%) OR (CI) No (%) OR (CI) years (range) p-value
14 ( n =60) Reference 11.7 3 (5) 1 8 (13) 1 8 (13) 1 35 (58) 1 10 (17) 1 70 (20–94) -----
1 ( n =14) 2.7 0 (0) ----- 0 (0) ----- 0 (0) ----- 4 (29) 0.31 (0.09-1.07) 0 (0) ----- 49 (32–68) <0.001
3 ( n =36) 7.0 9 (25) 6.33 (1.59–25.29) 11 (30) 2.86 (1.02–8.00) 8 (22) 1.86 (0.63–5.48) 30 (83) 3.82 (1.39–10.54) 15 (62) 3.57 (1.38–9.22) 75 (40–94) 0.530
4 ( n =55) 10.7 6 (11) 2.32 (0.55–9.79) 3 (55) 0.37 (0.09–1.49) 7 (13) 0.95 (0.32–2.81) 30 (55) 0.92 (0.44–1.92) 15 (27) 1.86 (0.76–4.62) 66 (20–91) 0.550
6A ( n =20) 3.9 0 (0) ----- 3 (15) 1.15 (0.27–4.82) 0 (0) ----- 14 (70) 1.78 (0.60–5.28) 11 (55) 6.11 (2.01–18.58) 73 (34–91) 0.669
6B ( n =24) 4.7 1 (4) 0.83 (0.08–8.36) 1 (4) 0,28 (0,03–2.39) 3 (12) 0.93 (0.22–3.84) 18 (75) 2.29 (0.80–6.59) 9 (37) 3.00 (1.03–8.74) 73 (34–97) 0.760
7F ( n =65) 12.7 7 (11) 2.29 (0.56–9.31) 6 (9) 0.66 (0.22–2.03) 12 (18) 1.47 (0.56–3.89) 33 (51) 0.74 (0.37–1.50) 16 (25) 1.63 (0.68–3.95) 63 (19–95) <0.001
8 ( n =18) 3.5 2 (11) 2.37 (0.36–15.46) 2 (11) 0,81 (0.15–4.22) 2 (11) 0.81 (0.16–4.22) 11 (61) 1.20 (0.41–3.53) 5 (28) 1.92 (0.56–6.61) 64 (49–86) 0.051
9V ( n =41) 8.0 4 (10) 2.05 (0.43–9.71) 4 (10) 0.70 (0.20–2.50) 8 (20) 1.58 (0.54–4.61) 27 (66) 1.42 (0.65–3.39) 10 (24) 1.61 (0.60–4.32) 69 (41–97) 0.381
18C ( n =16) 2.9 2 (12) 2.71 (0.41–17.83) 4 (25) 2.17 (0,56–8.40) 4 (25) 2.17 (0,56–8.40) 14 (88) 5.35 (1.12–25.66) 11 (69) 11.00 (3.13–38.64) 70 (37–85) 0.199
19A ( n =7) 1.4 0 (0) ----- 0 (0) ----- 1 (14) 1.08 (0.11–10.22) 6 (86) 4.59 (0.52–40.50) 2 (28) 2.00 (0.34–11.80) 70 (34–91) 0.845
19F ( n =16) 4.9 3 (19) 4.38 (0.79–24.24) 4 (25) 2.17 (0.56–8.39) 8 (50) 6.50 (1.90–22.25) 13 (81) 3.31 (0.85–12.85) 7 (44) 3.89 (1.17–12.89) 64 (24–91) 0.395
23F ( n =25) 4.9 0 (0) ----- 0 (0) ----- 1 (4) 0.27 (0.03–2.29) 21 (84) 4.1 (1.23–13.13) 12 (48) 4.61 (1.63–13.03) 73 (23–101) 0.835
  1. The 28 serotypes/serogroups with low incidence are not included in the table and were in descending order: 9N (n=11), 22 (n=11), 12 (n=10), 11 (n=9), 6C (n=9), 17 (n=4), 38 (n=4), 33 (n=4), 20 (n=4), 15 (n=3), 9A (n=3), 31 (n=3), 23A (n=3), 7 (n=3), 9 (n=3), 7A (n=2), 35 (n=2), 18 (n=2), 13 (n=2), 10 (n=2), 8F (n=1), 5 (n=1), 28 (n=1), 27 (n=1), 23B (n=1), 23 (n=1), 19 (n=1), and, finally, 18F (n=1). Ten isolates were nontypable (1.9%) and 4 isolates were missing.