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Table 1 Characteristics of patients with IPD by infecting serotype and statistical comparison in relation to infection with serotype 14

From: High incidence of septic shock caused by Streptococcus pneumoniae serotype 3 - a retrospective epidemiological study

 

Septic shock

28 day mortality

Admitted to the ICU

Any co-morbidity

Two or more co-morbidities per patient

Median age

Serotype (no)

Percent of all isolates

No (%)

OR (CI)

No (%)

OR (CI)

No (%)

OR (CI)

No (%)

OR (CI)

No (%)

OR (CI)

years (range)

p-value

14 ( n =60) Reference

11.7

3 (5)

1

8 (13)

1

8 (13)

1

35 (58)

1

10 (17)

1

70 (20–94)

-----

1 ( n =14)

2.7

0 (0)

-----

0 (0)

-----

0 (0)

-----

4 (29)

0.31 (0.09-1.07)

0 (0)

-----

49 (32–68)

<0.001

3 ( n =36)

7.0

9 (25)

6.33 (1.59–25.29)

11 (30)

2.86 (1.02–8.00)

8 (22)

1.86 (0.63–5.48)

30 (83)

3.82 (1.39–10.54)

15 (62)

3.57 (1.38–9.22)

75 (40–94)

0.530

4 ( n =55)

10.7

6 (11)

2.32 (0.55–9.79)

3 (55)

0.37 (0.09–1.49)

7 (13)

0.95 (0.32–2.81)

30 (55)

0.92 (0.44–1.92)

15 (27)

1.86 (0.76–4.62)

66 (20–91)

0.550

6A ( n =20)

3.9

0 (0)

-----

3 (15)

1.15 (0.27–4.82)

0 (0)

-----

14 (70)

1.78 (0.60–5.28)

11 (55)

6.11 (2.01–18.58)

73 (34–91)

0.669

6B ( n =24)

4.7

1 (4)

0.83 (0.08–8.36)

1 (4)

0,28 (0,03–2.39)

3 (12)

0.93 (0.22–3.84)

18 (75)

2.29 (0.80–6.59)

9 (37)

3.00 (1.03–8.74)

73 (34–97)

0.760

7F ( n =65)

12.7

7 (11)

2.29 (0.56–9.31)

6 (9)

0.66 (0.22–2.03)

12 (18)

1.47 (0.56–3.89)

33 (51)

0.74 (0.37–1.50)

16 (25)

1.63 (0.68–3.95)

63 (19–95)

<0.001

8 ( n =18)

3.5

2 (11)

2.37 (0.36–15.46)

2 (11)

0,81 (0.15–4.22)

2 (11)

0.81 (0.16–4.22)

11 (61)

1.20 (0.41–3.53)

5 (28)

1.92 (0.56–6.61)

64 (49–86)

0.051

9V ( n =41)

8.0

4 (10)

2.05 (0.43–9.71)

4 (10)

0.70 (0.20–2.50)

8 (20)

1.58 (0.54–4.61)

27 (66)

1.42 (0.65–3.39)

10 (24)

1.61 (0.60–4.32)

69 (41–97)

0.381

18C ( n =16)

2.9

2 (12)

2.71 (0.41–17.83)

4 (25)

2.17 (0,56–8.40)

4 (25)

2.17 (0,56–8.40)

14 (88)

5.35 (1.12–25.66)

11 (69)

11.00 (3.13–38.64)

70 (37–85)

0.199

19A ( n =7)

1.4

0 (0)

-----

0 (0)

-----

1 (14)

1.08 (0.11–10.22)

6 (86)

4.59 (0.52–40.50)

2 (28)

2.00 (0.34–11.80)

70 (34–91)

0.845

19F ( n =16)

4.9

3 (19)

4.38 (0.79–24.24)

4 (25)

2.17 (0.56–8.39)

8 (50)

6.50 (1.90–22.25)

13 (81)

3.31 (0.85–12.85)

7 (44)

3.89 (1.17–12.89)

64 (24–91)

0.395

23F ( n =25)

4.9

0 (0)

-----

0 (0)

-----

1 (4)

0.27 (0.03–2.29)

21 (84)

4.1 (1.23–13.13)

12 (48)

4.61 (1.63–13.03)

73 (23–101)

0.835

  1. The 28 serotypes/serogroups with low incidence are not included in the table and were in descending order: 9N (n=11), 22 (n=11), 12 (n=10), 11 (n=9), 6C (n=9), 17 (n=4), 38 (n=4), 33 (n=4), 20 (n=4), 15 (n=3), 9A (n=3), 31 (n=3), 23A (n=3), 7 (n=3), 9 (n=3), 7A (n=2), 35 (n=2), 18 (n=2), 13 (n=2), 10 (n=2), 8F (n=1), 5 (n=1), 28 (n=1), 27 (n=1), 23B (n=1), 23 (n=1), 19 (n=1), and, finally, 18F (n=1). Ten isolates were nontypable (1.9%) and 4 isolates were missing.