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Table 3 Evaluation of efficacy data obtained with three hand rubs according to different versions of ASTM E 1174

From: Less and less–influence of volume on hand coverage and bactericidal efficacy in hand disinfection

Product Volume Version of ASTM E 1174 Mean log10-reduction Neutralization in sampling fluid including validation Time between end of application and sampling Likelihood of false positive data Meets US FDA requirements Complete hand coverage
Purell Advanced Instant Hand Sanitizer 5 ml 1994 3.58* No No maximum High Yes Likely
2 ml 1994 3.35* No No maximum High Yes Likely
1.1 ml 2006 1.85** Yes Maximum: 60 s Very low No Unlikely
Purell Advanced Instant Hand Sanitizer Foam 5 ml 1994 3.55* No No maximum High Yes Likely
2 ml 1994 3.48* No No maximum High Yes Likely
1.1 ml 2006 1.60** Yes Maximum: 60 s Very low No Unlikely
Sterillium Comfort Gel 5 ml 1994 3.12* No No maximum High Yes Likely
2 ml 2006 2.06** Yes Maximum: 60 s Very low Yes Likely
  1. Methodological differences may explain conflicting results. *Data described by Edmonds et al. 2012 [8]; **data coming from this study.