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Table 3 Evaluation of efficacy data obtained with three hand rubs according to different versions of ASTM E 1174

From: Less and less–influence of volume on hand coverage and bactericidal efficacy in hand disinfection

Product

Volume

Version of ASTM E 1174

Mean log10-reduction

Neutralization in sampling fluid including validation

Time between end of application and sampling

Likelihood of false positive data

Meets US FDA requirements

Complete hand coverage

Purell Advanced Instant Hand Sanitizer

5 ml

1994

3.58*

No

No maximum

High

Yes

Likely

2 ml

1994

3.35*

No

No maximum

High

Yes

Likely

1.1 ml

2006

1.85**

Yes

Maximum: 60 s

Very low

No

Unlikely

Purell Advanced Instant Hand Sanitizer Foam

5 ml

1994

3.55*

No

No maximum

High

Yes

Likely

2 ml

1994

3.48*

No

No maximum

High

Yes

Likely

1.1 ml

2006

1.60**

Yes

Maximum: 60 s

Very low

No

Unlikely

Sterillium Comfort Gel

5 ml

1994

3.12*

No

No maximum

High

Yes

Likely

2 ml

2006

2.06**

Yes

Maximum: 60 s

Very low

Yes

Likely

  1. Methodological differences may explain conflicting results. *Data described by Edmonds et al. 2012 [8]; **data coming from this study.