Association between tuberculin skin test result and clinical presentation of tuberculosis disease

BMC Infectious Diseases

Table 3 Association between TST result and sputum smear result for AFB among persons with culture-confirmed pulmonary TB, stratified by HIV status and birthplace and adjusted for age and sex (N = 46,680)

		Non-cavitary pulmonary disease				Cavitary pulmonary disease
		Total	Smear-positive (%)	aOR*	95% CI*	Total	Smear-positive (%)	aOR	95% CI
HIV+/US
	0–4 mm	1,073	651 (61)	Ref		183	135 (74)	Ref
	5–9 mm	79	44 (56)	0.78	0.49, 1.24	16	14 (88)	2.66	0.58, 12.27
	10–14 mm	603	317 (53)	0.72	0.59, 0.88	139	117 (84)	1.90	1.08, 3.35
	≥ 15 mm	1,182	545 (46)	0.56	0.47, 0.66	320	245 (77)	1.15	0.75, 1.75
	Sub-total	2,937	1,557 (53)			658	511 (78)
HIV+/FB
	0–4 mm	522	325 (62)	Ref		62	48 (77)	Ref
	5–9 mm	36	24 (67)	1.20	0.59, 2.47	7	4 (57)	0.37	0.07, 1.86
	10–14 mm	267	140 (52)	0.67	0.50, 0.91	61	37 (61)	0.45	0.20, 1.00
	≥ 15 mm	483	217 (45)	0.50	0.39, 0.65	130	102 (78)	1.03	0.49, 2.16
	Sub-total	1,308	706 (54)			260	191 (73)
HIV-/US
	0–4 mm	2,051	1,195 (58)	Ref		1,430	1,232 (86)	Ref
	5–9 mm	285	159 (56)	0.89	0.69, 1.14	273	236 (86)	0.99	0.68, 1.44
	10–14 mm	2,759	1,504 (55)	0.84	0.74, 0.94	2,137	1,795 (84)	0.78	0.64, 0.95
	≥ 15 mm	7,576	3,745 (49)	0.69	0.62, 0.76	5,960	5,027 (84)	0.80	0.68, 0.95
	Sub-total	12,671	6,603 (52)			9,800	8,290 (85)
HIV-/FB
	0–4 mm	831	468 (56)	Ref		600	482 (80)	Ref
	5–9 mm	314	159 (51)	0.78	0.60, 1.02	180	150 (83)	1.23	0.79, 1.91
	10–14 mm	2,702	1,338 (50)	0.74	0.63, 0.87	1,790	1,466 (82)	1.10	0.87, 1.39
	≥ 15 mm	7,992	3,626 (45)	0.62	0.54, 0.72	4,637	3,754 (81)	1.03	0.83, 1.28
	Sub-total	11,839	5,591 (47)			7,207	5,852 (81)
Total		28,755	14,457 (50)			19,925	14,844 (83)

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