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Table 2 Minimum inhibitory concentration (MIC) for second-line drugs (N = 22 isolates)

From: Application of quantitative second-line drug susceptibility testing at a multidrug-resistant tuberculosis hospital in Tanzania

Drug Susceptible (% N) Borderline susceptible (% N) Resistant (% N)
[MIC range] [MIC range] [MIC range]
Kanamycin 11 (50) 10 (45) 1 (5)
[≤0.6-1.2 μg/ml] [2.5-5.0 μg/ml] [>40.0 μg/ml]
Amikacin 15 (68) 6 (27) 1 (5)
[≤0.12-0.25 μg/ml] [≤0.5-1.0 μg/ml] [16 μg/ml]
Ofloxacina 12 (55) 10 (45) 0
[≤0.25-0.5 μg/ml] [1.0-2.0 μg/ml] N/A
Moxifloxacin 11 (50) 10 (45) 1 (5)
[≤0.6 μg/ml] [≤0.12-0.25 μg/ml] [0.5 μg/ml]
Ethionamide 11 (50) 8 (36) 3 (14)
[0.5-1.2 μg/ml] [2.5-5.0 μg/ml] [10.0-40.0 μg/ml]
Cycloserine 17 (77) 5 (23) 0
[1.2-8.0 μg/ml] [16.0-32.0 μg/ml] N/A
PAS 15 (68) 2 (9) 5 (23)
[≤0.5 μg/ml] [1.0 μg/ml] [8.0- >64.0 μg/ml]
Rifabutin 9 (41) 0 13 (59)
[≤0.12 μg/ml] N/A [1.0- >16.0 μg/ml]
  1. PAS para-aminosalicylic acid. aPatients received ofloxacin or levofloxacin. Moxifloxacin and rifabutin were not available on formularly.