Table 2 Association of HIV/HCV group with concurrently elevated (>75th percentile) inflammatory biomarkers
Model A (N = 218) | Unadjusted | Adjusteda | ||
|---|---|---|---|---|
| Â | POR(95% CI) | p-value | POR(95% CI) | p-value |
Undetectable | 1 | -- | 1 | -- |
  HIV mono-detectable | 1.89 (1.03, 3.46) | 0.04 | 1.52 (0.68, 3.41) | 0.31 |
  HCV mono-detectable | 2.70 (1.29, 5.68) | <0.01 | 2.95 (1.08, 8.01) | 0.03 |
  HIV/HCV detectable | 3.48 (1.87, 6.46) | <0.01 | 2.49 (1.05, 5.89) | 0.04 |
FIB-4 ≥ 1.45 | -- | -- | 2.56 (1.39, 4.35) | <0.01 |
High cholesterol | -- | -- | 1.74 (0.97, 3.14) | 0.06 |
Age greater than median (42 yrs) | -- | -- | 0.61 (0.36, 1.04) | 0.07 |
BMI ≥ 30 kg/m2 | -- | -- | 1.81 (0.93, 3.54) | 0.08 |
Ever smoker | -- | -- | 1.53 (0.85, 2.78) | 0.16 |
CD4 > 200 cells/mm3 | -- | -- | 0.63 (0.31, 1.26) | 0.19 |
Renal disease | -- | -- | 2.15 (0.67, 6.86) | 0.20 |
Diabetes | -- | -- | 1.90 (0.58, 6.21) | 0.29 |
Current antiretroviral therapy use | -- | -- | 0.74 (0.42, 1.31) | 0.30 |
Prevalent cardiovascular disease | -- | -- | 1.82 (0.56, 5.97) | 0.32 |
Hypertension | -- | -- | 0.78 (0.42, 1.45) | 0.44 |
At-risk alcohol consumption | -- | -- | 0.94 (0.55, 1.62) | 0.83 |
Female | -- | -- | 1.03 (0.55, 1.94) | 0.93 |