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Table 1 Incidence of anogenital warts

From: Systematic review of the incidence and prevalence of genital warts

Study Country / Year Setting, population and age groups Annual incidence per 100,000 Definitions
    New Recurrent Any (including new and recurrent)  
Data based on retrospective administrative databases or medical chart reviews
Pirotta et al., 2010 [27] Australia / 2000-06 Setting: nationally representative random sample of approximately 6,460 practicing GPs and sexual health clinics NA NA Overall: 219 Males: 206 Females: 231 Any: GW cases never managed by any doctor or a first medical consultation for a new episode of a recurrent problem as determined by GP at consultation
Population: general population  
Age: all ages  
Steben et al., 2011 [31] Canada (Quebec) / 2007 (data for most recent year) Setting: provincial, public healthcare system Males: 103 Females: 98 NA NA New: GW cases preceded by a 12-month, disease-free period of GW care
Population: population covered by the public drug plan (41% of total population)  
Age: all ages  
Marra et al., 2009 [32] Canada (British Columbia) / 1998-2006 Setting: physicians, hospitals and STI clinics (province-wide) Overall: 126 Males: 131 Females: 121 NA NA New: GW cases preceded by a 12-month, disease-free period of GW care
Denominator: general population  
Age: all ages    
Kliewer et al., 2009 [33] Canada (Manitoba) / 2004 Setting: physician offices and hospitals (province-wide) Males: 154 Females: 120 NA NA New: GW cases preceded by a 12-month, disease-free period of GW care
Population: general population  
Age: all ages  
Kraut et al., 2010 [34] Germany / 2005-06 Setting: physician offices and hospitals Overall: 170 Males: 148 Females: 191 NA NA New: GW cases preceded by a 12-month, disease-free period of GW care
Population: a sample of the German population with statutory health insurance covering all geographical regions (N = 14 million)  
Age: 10–79 years  
Vittori et al., 2008 [28] Italy / 2005 Setting: random sample of 78 gynecologists stratified by geographic region Females: 430 Females: 110 (early); 60 (late) NA New: patients without previous history of GWs. Early recurrent: patients who had a GW episode within the previous 12 months
Population: female population visiting gynecologists Late recurrent: patients who had a GW episode more than 12 months prior to study episode
Age: 14–64 years  
van den Broek et al., 2010 [39] Netherlands / 2006 Setting: GPs (representative national sample) and all Dutch STI centers NA NA Males: 94* Females: 137* Any: patients with symptoms of GWs
Population: general population  
Age: all ages  
Castellsague et al., 2009 [29] Spain / 2005 Setting: representative sample of dermatologists, gynecologists and urologists in the public healthcare setting from 6 autonomous regions Overall: 118 Males: 137 Females: 100 Overall: 43 Males: 47 Females: 39 Overall: 160 Males: 184 Females: 137 New: patients without any prior GW diagnosis
Population: general population (68% of total Spanish population)     Recurrent: patients who had a previous GW episode
Age: 14–64 years    
Cassell et al., 2006 [40] UK / 1998-2000 Setting: representative sample of GPs and GUM clinics NA NA Males: 308 Females: 236 Any: all patients diagnosed with GWs
Population: general population  
Age: all ages  
Desai et al., 2011 [38] UK (England) / 2006-2009 Setting: representative sample of GPs and all GUM clinics Overall: 157 Males: 168 Females: 142 Overall: 133 Males: 163 Females: 103 Overall: 289 Males: 331 Females: 245 New: patients diagnosed with GWs for the first time during study period
Population: general population     Recurrent: episode occurring more than 8 weeks after last attendance
Age: all ages    
Hoy et al., 2009 [35] USA / 2004 Setting: physicians, hospitals, ERs reimbursed by 5 geographically dispersed private health plans Overall: 120 Males: 110 Females: 120 NA NA New: individuals not having a medical or pharmacy claim associated with GWs in the previous 12 months to the index medical claim
Population: privately-insured population (N = 3.8 million)  
Age: all ages  
Insinga et al., 2003 [2] USA / 2000 Setting: physicians, hospitals, ERs reimbursed by private health plans NA NA Overall: 170 Males: 167 Females: 165 Any: all patients diagnosed with GWs
Population: privately-insured population (N = 3.7 million)  
Age: all ages  
Koshiol et al., 2004 [36] USA / 2001 Setting: physicians, hospitals, ERs reimbursed by approximately 30 private health plans (national) Overall: 205 NA NA New: no GW-related claims during the initial 12 months of continuous enrollment
Population: privately-insured population (N = 5.9 million)
Age: 15–59 years
Data based on prospectively collected physician reports
Lin et al., 2010 [30] China (Hong Kong) / 2009 Setting: sample of 170 physicians operating in private clinics (GPs, obstetricians/gynecologists and dermatologists/venereologists) and all 5 local social hygiene clinics Overall: 204 Males: 292 Females: 125 NA NA New: cases with no past symptoms or clinical diagnosis of GWs
Population: general population  
Age: ≥18 yrs  
Monsonego et al., 2007 [43] France / 2005 Setting: nationwide random sample of 212 gynecologists Females: 176 Females: 48 Females: 229 NA
Population: general female population
Age: 15–65 years
Hillemanns et al., 2008 [37] Germany / 2005 Setting: representative sample of 129 gynecologists Females: 114 (age 14–65); 76 (all ages) Females: 35 (age 14–65); 23 (all ages) Females: 149 (age 14–65); 99 (all ages) New: patients diagnosed with GWs at the time of the visit
Population: general female population Recurrent: patients with previous episodes of GWs that had resolved
Age: 14–65 years and all ages Resistant: patients with previous episodes of GWs that had not resolved with treatment
Pasciullo et al., 2011 [41] Italy / 2009 Setting: geographically representative sample of 650 GPs NA NA Overall: 8 Males: 10 Females: 4 Any: all patients diagnosed with GWs
Population: population listed with the above GPs (N = 959,778)  
Age: ≥15 years  
Data based on genital examinations of samples from the general population
Anic et al., 2011 [8] Multinational (USA, Mexico, Brazil) / 2005-2009 Setting: prospective study investigating the natural history of HPV infection in men (HPV in Men study) Males: 235 NA NA NA
Population: males with no previous history of GW participating in the above study (N = 2,487)
Age: 18–70 years
Sasagawa et al., 2011 [42] Japan / 2009 Setting: 63 private clinics in 5 districts NA NA Females: 251 NA
   Population: women attending Pap screening in above private clinics (N = 60,414)     
   Age: 10–59 years     
  1. AGWs anogenital warts, ER emergency room, GP general practitioner, GUM genitourinary medicine, GWs genital warts, N number of individuals examined or followed, NA not available, STI sexually transmitted infection.
  2. * GP and STI center rates combined.
  3. †About 90% of the German population is covered by the statutory health insurance [34].