|
Demographic information
| | | |
|
Age
| | | |
|
0-30
|
32 (51.6)
|
55 (64.0)
|
0.132
|
|
>30
|
30 (48.4)
|
31 (36.0)
| |
|
Gender, M:F (ratio)
|
29:33 (46.8)
|
59:27 (68.6)
|
0.008
|
|
Medical history
| | | |
|
Smoking
|
7 (12.5)
|
16 (19.5)
|
0.278
|
|
Alcohol
|
1 (1.7)
|
3 (3.7)
|
0.479
|
|
Steroid treatment
|
2 (3.3)
|
7 (8.3)
|
0.222
|
|
Respiratory failure
|
0 (0)
|
3 (3.5)
|
0.138
|
|
Personal history of furuncles or skin abscess
|
1 (2.0)
|
12 (16.0)
|
0.011
|
|
Before hospital admission
|
|
Period between onset of symptoms and admissiona
|
3 (2-4)
|
3 (2-5)
|
0.684
|
|
Influenza-like illness
|
46 (79.3)
|
41(49.4)
|
<0.001
|
|
SSTIb
|
6 (9.7)
|
27 (31.4)
|
0.002
|
|
Clinical features within the first 48 h of hospitalization
| |
|
PRISM scorea, b
|
27 (20-35)
|
6 (4-11)
|
<0.001
|
|
SAPS II scorea, b
|
67 (39-80)
|
28 (15-61.8)
|
<0.001
|
|
Platelet count/mL
|
92,000 (46,500-176,500)
|
204,000 (145,000-370,000)
|
<0.001
|
|
Fever, temperature >39°C
|
46 (64.2)
|
70 (81.4)
|
0.294
|
|
Generalized rash 24 h
|
5 (8.3)
|
6(7.0)
|
0.760
|
|
Airway hemorrhage
|
39 (62.9)
|
20 (23.3)
|
<0.001
|
|
Pleural effusion
|
16 (27.1)
|
49 (57.6)
|
<0.001
|
|
Radiological consolidation
| | |
0.001
|
|
Unilobar
|
6 (9.8)
|
30 (34.9)
| |
|
Multilobar
|
48 (78.7)
|
44 (51.2)
| |
|
ARDSb
|
47 (77.0)
|
15 (18.1)
|
<0.001
|
|
Methicillin resistance (mecAgene)
|
15 (24.2)
|
20 (23.3)
|
0.895
|
|
Treatment and outcome
|
|
Mechanical ventilation
|
57 (91.9)
|
37 (43.0)
|
<0.001
|
|
Inotrope drugs
|
52 (91.2)
|
21 (26.3)
|
<0.001
|
|
Time to deatha
|
2 (1-6)
|
2 (1-2.75)
|
0.216
|
|
Appropriate antibiotics introduced in first 24 h of h hospitalization
|
46 (75.4)
|
65 (75.6)
|
0.161
|
|
Mortality
|
47 (75.8)
|
14 (16.3)
|
<0.001
|
|
Percentage of deaths attributed to S. aureus infection
|
47 (100)
|
13 (92.9)
|
0.065
|
