Species (No of isolates) | Antifungal agent | MIC (μg/ml) | % Resistant | ||
---|---|---|---|---|---|
Range | MIC50 a | MIC90 a | |||
All isolates (240) | Fluconazole | 1– > 128 | 1 | 4 | 7.5 |
Voriconazole(except C. glabrata) | 0.06– > 8 | 0.064 | 0.25 | 5.4 | |
Itraconazole(limit C.albicans only) | 0.125– > 4 | 0.125 | 0.5 | 4.9 | |
Caspofunginb | 0.032–2 | 0.125 | 0.5 | 0 | |
Flucytosine | < 4–16 | 4 | 4 | ||
Amphotericin B | < 0.5–0.5 | 0.5 | 0.5 | ||
C. albicans (136) | Fluconazole | 1– > 128 | 1 | 2 | 6.6 |
Voriconazole | 0.06– > 8 | 0.064 | 0.064 | 2.9 | |
Itraconazole | 0.125– > 4 | 0.125 | 0.125 | 4.9 | |
Caspofunginb | 0.032–0.38 | 0.094 | 0.19 | 0 | |
Flucytosine | < 4–16 | 4 | 4 | ||
Amphotericin B | < 0.5–0.5 | 0.5 | 0.5 | ||
C.tropicalis (59) | Fluconazole | 1– > 128 | 1 | 128 | 10.6 |
Voriconazole | 0.06– > 8 | 0.064 | 8 | 10.6 | |
Itraconazole | 0.125– > 4 | 0.125 | 4 | ||
Caspofunginb | 0.032–0.38 | 0.094 | 0.19 | 0 | |
Flucytosine | < 4–4 | 4 | 4 | ||
Amphotericin B | < 0.5–0.5 | 0.5 | 0.5 | ||
C. paraps-ilosis (25) | Fluconazole | < 1–2 | 1 | 1 | 0 |
Voriconazole | < 0.06–0.25 | 0.064 | 0.064 | 0 | |
Itraconazole | < 0.125–0.25 | 0.125 | 0.125 | ||
Caspofunginb | 0.38–2 | 1 | 1.5 | 0 | |
Flucytosine | < 4– > 16 | 4 | 16 | ||
Amphotericin B | < 0.5–0.5 | 0.5 | 0.5 | ||
C.glabrata (20) | Fluconazole | 1–64 | 2 | 64 | 15.0 |
Voriconazole | 0.06–8 | 0.125 | 8 | ||
Itraconazole | 0.125– > 4 | 0.5 | 4 | ||
Caspofunginb | 0.047–0.38 | 0.19 | 0.25 | 0 | |
Flucytosine | < 4–4 | 4 | 4 | ||
Amphotericin B | < 0.5–0.5 | 0.5 | 0.5 |