Skip to main content

Table 1 Patient characteristics and incidence (episode/1000 admission)

From: Surveillance study of species distribution, antifungal susceptibility and mortality of nosocomial candidemia in a tertiary care hospital in China

  Candidaspecies
  Total C. tropicalis C. albicans C. parapsilosis C. glabrata C. krusei C. guilliermondii Other*
  (n = 133) (n = 38) (n = 31) (n = 26) (n = 11) (n = 3) (n = 6) (n = 18)
  100.0% 28.6% 23.3% 19.5% 8.3% 2.3% 4.5% 13.5%
Patients characteristic         
Age (years)         
1-14 3(2.3) 1(33.3) 1(33.3) 0(0) 0(0) 0(0) 0(0) 1(33.3)
15-49 29(21.8) 7(24.1) 9(31.0) 5(17.2) 3(10.3) 0(0) 1(3.4) 4(13.8)
50-65 40(30.1) 13(32.5) 7(17.5) 8(20.0) 3(7.5) 1(2.5) 4(10.0) 4(10.0)
>65 61(45.9) 17(27.9) 14(23.0) 13(21.3) 5(8.2) 2(3.3) 1(1.6) 9(14.8)
Gender         
Male 91(68.4) 28(30.8) 20(22.0) 18(19.8) 6(6.6) 2(2.2) 2(2.2) 15(16.5)
Female 42(31.6) 10(23.8) 11(26.2) 8(19.0) 5(11.9) 1(2.4) 4(9.5) 3(7.1)
Underline diseases n (%)         
Intestinal fistula/abdominal infection 74(55.7) 14(18.9) 20(27.0) 15(20.3) 6(8.1) 3(4.1) 5(6.8) 11(14.9)
Solid tumor 8(6.0) 2(25.0) 2(25.0) 1(12.5) 2(25.0) 0(0) 0(0) 1(12.5)
Respiratory dysfunctiona 17(12.8) 11(64.7) 3(17.6) 1(5.9) 0(0) 0(0) 0(0) 2(11.8)
Gastrointestinal pathologyb 14(10.5) 4(28.6) 1(7.1) 5(35.7) 1(7.1) 0(0) 1(7.1) 2(14.3)
Haematological malignancy 6(4.5) 5(83.3) 1(16.7) 0(0) 0(0) 0(0) 0(0) 0(0)
Acute renal failurec 11(8.3) 1(9.1) 3(27.3) 4(36.4) 2(18.2) 0(0) 0(0) 1(9.1)
Burns 3(2.3) 1(33.3) 1(33.3) 0(0) 0(0) 0(0) 0(0) 1(33.3)
Receipt of corticosteroids 76(57.1) 21(27.6) 17(22.4) 15(19.7) 5(6.6) 1(1.3) 2(2.6) 15(19.7)
Chemotherapy 6(4.5) 5(83.3) 1(16.7) 0(0) 0(0) 0(0) 0(0) 0(0)
Presence of CVCd 61(45.9) 19(31.1) 13(21.3) 11(18.0) 5(8.2) 2(3.3) 4(6.6) 7(11.5)
Parenteral nutrition 61(45.9) 20(32.8) 18(29.5) 6(9.8) 8(13.1) 1(1.6) 3(4.9) 5(8.2)
Mechanical ventilation 17(12.8) 6(35.3) 5(29.4) 2(11.8) 2(11.8) 0(0) 0(0) 2(11.8)
In the ICU at diagnosis 39(29.3) 14(35.9) 9(23.1) 8(20.5) 3(7.7) 2(5.1) 0(0) 3(7.7)
Neutropeniae 6(4.5) 2(33.3) 2(33.3) 0(0) 2(33.3) 0(0) 0(0) 0(0)
Dialysis 2(1.5) 0(0) 1(50.0) 1(50.0) 0(0) 0(0) 0(0) 0(0)
Exposition to antibiotics 80(60.2) 29(36.3) 23(28.8) 20(25.0) 3(3.8) 2(2.6) 1(1.3) 2(2.6)
Treatment with fluconazole 61(45.9) 23(37.7) 18(29.5) 5(8.2) 3(4.9) 3(4.9) 2(3.3) 7(11.5)
Incidence (episodes/1000 admissions)         
2009 0.71 0.19 0.22 0.11 0.06 0.02 0.04 0.06
2010 0.77 0.18 0.15 0.23 0.02 0.03 0.03 0.15
2011 0.85 0.31 0.19 0.13 0.13 0 0.03 0.12
  1. *Others include: C. pelliculosa(8), C. famata(7) and C. haemulonii(2).
  2. aIncludes the following diseases: pneumonia, chronic obstructive pulmonary disease, and acute respiratory distress syndrome.
  3. bIncludes the following diseases: cholecystitis, pancreatitis, peritonitis, and hepatitis.
  4. cAcute renal failure was defined as sudden and often temporary loss of kidney function with nitrogen waste retention and hypourocrinia.
  5. d CVC central venous catheter.
  6. eNeutropenia was defined as absolute neutrophil count <500 cells/μl.