Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: evidence of possible mediation by host tRNA-derived small noncoding RNAs

Table 3 The predicted interactors to the two tRF-5s.

tRF	Gene name [accession number]	ΔG value (Kcal/mol)
tRF5-ValGTG	Homo sapiens protein kinase C, beta (PRKCB), transcript variant 1, mRNA [NM_121535.2]	-34.2
	Homo sapiens carboxyl ester lipase (bile salt-stimulated lipase) (CEL), mRNA [NM_001807.3]	-35.3
	HOMO sapiens glutamyl-tRNA synthetase 2, mitochondrial (EARS2), transcript variant 1, mRNA [NM_001083614.1]	-40.2
	HOMO sapiens solute carrier family 23 (nucleobase trnasporters), member 2 (SLC23A2), trnascript variant 1, mRNA [NM_005116.5]	-36.9
tRF5-GlyGCC	Homo sapiens long interegenic non-protein coding RNA 317 (LINC00317), non-coding RNA [NR_038872.1]	-50.6
	Homo sapiens SH3-domain GRB2-like endophilin B1 (SH3GLB1), transcript variant 1, mRNA [NM_016009.4]	-37.3
	Homo sapiens glial cells missing homolog 1 (drosophila) (GMC1), mRNA [NM_016009.4]	-37.2
	Homo sapiens syntrophi, beta 1 (dystrophin-asociated protein A1, 59kDa, basic component 1) (SNTB1) mRNA [NM_021021.3	-39.7

The potential target mRNAs of the two tRF-5s and their interactions are summarized and tabulated. In the depicted base-pairing interactions, the sequences on the top and bottom are tRF-5 and its predicted target mRNA, respectively. The numbers of target mRNAs indicate nucleotide coordinates of the RefSeq shown in the second column. The degree of interaction, expressed in ∆ G values, was calculated by the RNAhybrid program and shown.

ISSN: 1471-2334