Figure 3

Expression of cell surface antigens on macrophages at two different time points. Compared with the control group on day 1, day 9 macrophages infected with M. leprae and co-cultured with T lymphocytes showed relatively higher expression of CD14, CD163 and CD206. While in macrophages infected with M. leprae, the expression level of CD14, CD68, CD163, TLR4, CD86 and CD206, were downregulated as compared to those infected macrophages co-cultured with PBMCs. Representative data of one donor, from three independent experiments are shown. P-values were calculated using the Welch unpaired t-test in comparison with day 1 macrophages.