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Table 4 Univariate analysis of the association between subclinical atherosclerosis and other factors related to HIV, by age group, seen at two referral hospitals in the state of Pernambuco, Brazil

From: Risk factors for subclinical atherosclerosis in HIV-infected patients under and over 40 years: a case–control study

Variables < 40 years old (n=351) ≥ 40 years old (n=346)
% subclinical atherosclerosis OR(CI) p-value % subclinical atherosclerosis OR(CI) p-value
Time elapsed since HIV diagnosis (years )       
< 1 19.3 1.0 - 55.1 1.0 -
1 to < 5 22.3 1.19 (0.64 – 2.25) 0.570 65.8 1.56 (0.81 – 3.01) 0.179
≥5 30.5 1.82 (0.91 – 3.66) 0.090 70.6 1.95 (0.99 – 3.83) 0.051
Clinical history of AIDS       
No 24.0 1.0 - 65.7 1.0 -
Yes 24.2 1.01 (0.58 – 1.76) 0.975 72.7 1.38 (0.68 – 2.81) 0.362
CD4+ T-lymphocytes (cells/mm 3 )       
< 200 22.2 1.0 - 53.3 1,0 -
200 to < 350 24.4 1.12 (0.51 – 2.48) 0.763 63.1 1.49 (0.81 – 2.74) 0.193
350 and more 21.9 0.98 (0.42 – 2.30) 0.963 84.0 4.59 (2.19 – 9.59) 0.000
Viral load (copies/mL)       
< 50 29.4 1.0 - 67.5 1.0 -
50 to < 10,000 24.6 0.78 (0.34 – 1.81) 0.566 62.7 0.89 (0.41-1.91) 0.767
10,000 < 100,000 19.4 0.58 (0.21 – 1.61) 0.295 72.7 1.61 (0.54-4.73) 0.384
> 100,000 15.4 0.44 (0.09 – 2.21) 0.316 68.6 1.07 (0.32-3.55) 0.905
HAART use       
No 19.9 1.0 - 59.5 1.0 -
Yes 26.0 1.42 (0.85 – 2.36) 0.184 68.9 1.50 (0.91 – 2.48) 0.109
Types HAART regimens       
No HAART use 19.9 1.0 - 59.5 1.0 -
PI 17.1 0.83 (0.40 – 1.71) 0.619 59.3 0.99 (0.54 – 1.79) 0.977
NNRTI 31.2 1.83 (1.05 – 3.19) 0.031 74.2 1.95 (1.12 – 3.39) 0.017
HAART duration of use (years)       
No HAART use 19.9 1.0 - 59.5 1.0 -
< 5 24.7 1.32 (0.78 - 2.25) 0.299 64.2 1.21 (0.72 – 2.06) 0.460
≥ 5 34.6 2.13 (0.86 – 5.27) 0.100 81.6 3.00 (1.46 – 6.16) 0.003