| |
Neuropsychiatric disorders (No)
|
Neuropsychiatric disorders (Yes)
|
|---|
| |
EFV only
|
EFV + RIF
|
EFV only
| |
EFV + RIF
|
|---|
|
N
|
Median (IQR)
|
N
|
Median (IQR)
|
N
|
Median (IQR)
|
N
|
Median (IQR)
|
|---|
|
Day-3
|
15
|
2.29 (1.41-2.88)
|
22
|
1.48 (1.15-1.88)
|
41
|
2.6 (2.09-2.94)
|
84
|
1.97 (1.38-2.91)
|
|
week-1
|
13
|
2.25 (1.84-2.69)
|
15
|
1.53 (1.28-1.97)
|
39
|
2.47 (2.09-3.23)
|
41
|
1.9 (1.34-2.61)
|
|
week-2
|
15
|
1.9 (1.27-2.3)
|
25
|
1.66 (1.36-2.11)
|
37
|
2.51 (1.84-3.43)
|
74
|
2.05 (1.4-2.67)
|
|
week-4
|
12
|
1.64 (1.46-2.43)
|
28
|
1.57 (1.19-2.17)
|
36
|
2.65 (2.05-3.56)
|
74
|
2.37 (1.55-3.57)
|
|
week-6
|
12
|
2.11 (1.46-3.41)
|
24
|
1.77 (1.37-2.02)
|
25
|
2.43 (1.94-3.51)
|
61
|
2.17 (1.66-4.63)
|
|
week-8
|
14
|
1.69 (1.41-2.49)
|
31
|
1.56 (1.34-3.05)
|
35
|
2.48 (2.23-3.13)
|
86
|
1.91 (1.48-3.22)
|
|
week-12
|
12
|
1.86 (1.45-2.26)
|
29
|
1.84 (1.45-2.7)
|
31
|
2.61 (2.04-4.09)
|
70
|
2.29 (1.56-4.45)
|
- No significant difference in EFV concentrations between treatment groups was observed.
