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Table 1 Baseline characteristics (demographics, measures of HIV disease and neuropsychiatric symptoms of HIV-only and HIV-TB co-infected (Rifampicin treatment) study participants at initiation of ART

From: Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without tuberculosis: a prospective cohort study

Baseline demographics and measures of HIV disease

All participants (n=197)

HIV- patients (n=59)

HIV-TB patients (n=138)

P-value

Proportion of female participants

109 (55.3)

40 (67.8)

69 (50.4)

0.02

Body weight at ART initiation / kg (±SD)

53.6± 10.1

56.5 ± 9.8

51.9± 10.0

0.015

Age / years (±SD)

33.8± 7.2

36.5 ± 6.1

32.7±7.4

0.003

Initial CD4 count (±SD)

97.2± 77.4

123.1± 63.7

86.2± 79.9

0.009

Log10. viral load (±SD)

4.95± 0.71

4.81± 0.73

5.02± 0.70

0.08

Baseline neuropsychiatric Symptoms

61 (31)

14 (23.7 )

47 (34.1)

0.14

Sleep disorders

36 (18.3)

9(15.2)

27 (19.7)

0.46

Insomnia

21 (10.7)

6(10.2)

15(10.9)

0.88

Vivid dreams

11 (5.6)

4(6.9)

7(5.2)

0.66

Sleep walking

9 (4.6)

0(0.0)

9 (6.67)

0.04

Hallucinations

3(1.5)

1(1.7)

2(1.5)

0.9

   Auditory

3(1.5)

1(1.7)

2(1.5)

0.9

   Visual

0(0.0)

0(0.0)

0(0.0)

-

   Tactile

0(0.0)

0(0.0)

0(0.0)

-

Cognitive disorder

46 (23.4)

9(15.2)

37 (27.0)

0.07

  1. SD standard deviation.