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Table 2 Point estimates for relationship between risk of infection in unvaccinated population and vaccine coverage

From: An approximation of herd effect due to vaccinating children against seasonal influenza – a potential solution to the incorporation of indirect effects into static models

A. Effective coverage in children 0.0% 21.00% 35.00% 45.65% 49.00% 60.00% 62.30%
Proportion of children in the total population, for estimating B.   25.78% [24] 25.78% [24] 35.70% [11] 25.78% [24] 21.08% [29] 25.78% [24]
B. Change in effective coverage in entire population (induced by varying levels of effective coverage in children) 0.0% 5.41% 9.02% 16.30% 12.63% 12.65% 16.06%
Study and population analysed        
Vynnycky et al. (2008) [29] 1.00      0.44  
Influenza A, 15–44 years, minimum
Vynnycky et al. (2008) [29] 1.00      0.05  
Influenza A, 15–44 years, maximum
Loeb et al. (2010) [11] 1.00    0.39    
Entire (unvaccinated) population
Halloran et al. (2002) [24] 1.00 0.80 0.59   0.42   0.29
Unvaccinated children
Halloran et al. (2002) [24] 1.00 0.77 0.58   0.41   0.28
Adults
RR estimates from fitted general linear equation        
A. In unvaccinated remainder of children * 1.00 0.75 0.58 0.45 0.41 0.28 0.25
B. In other age groups ** 1.00 0.75 0.58 0.24 0.41 0.41 0.25
  1. Point estimates for relationship between relative risk of infection in unvaccinated population as a function of (A) effective coverage in children, and (B) change in effective vaccine coverage in entire population induced by varying levels of effective coverage in children, and the corresponding RR estimates from the fitted general linear equations.
  2. *RR unvaccinated children  = 1–1.2031*effective coverage in children.
  3. **RR other age groups  = 1–4.6656*(effective coverage in children)* P children .