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Table 4 Performance of biochips in comparison with DST

From: Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays

Biochip resulta Number of isolates with the indicated result
OFX LVX MFX KAN CAPb XDR
R S R S R S R S R S R S
R 41 0 24 17 40 1 33 2 16 1 26 2
S 1 23 0 24 0 24 1 29 0 48 2 37
Sensitivity (%) 98 100 100 97 100 93
Specificity (%) 100 59 98 94 94 95
  1. a - R, isolates with mutations in gyrA, gyrB (FQ), rrs(KAN and CAP), eis(KAN); S, isolates without mutations.
  2. b - Isolates with mutations in eis were considered sensitive in biochip analysis.