Skip to main content

Table 2 Correlation of detected mutations in the rrs and eis genes with phenotypic DST

From: Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays

Gene (mutation) No. of isolates MIC Bactec MGIT 960 (mg/L)
KAN CAP
rrs (a1401g) 17 >80 3-20
eis (g-10a) 10 5 to >80 0.6 to 2.5
eis (c-12t) 2 1.3 to 5 1.3
eis (c-14t) 2 20 1.3
1 0.63 1.3
eis (g-37t) 3 10 to 20 1.3 to 2.5
No mutation 29 0.3 to 2.5 0.6 to 2.5
1 5 1.3
(H37Rv) 2.5 2.5
  1. The MICs considered to reflect resistance are highlighted in bold.