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Table 4 Frequency of HLA-A, -B and –DRB1 alleles in ACL subgroup 1A and control group

From: Association between HLA genes and American cutaneous leishmaniasis in endemic regions of Southern Brazil

  ACL (group 1A) (n = 118) Controls (n = 260)       ACL (group 1A) (n = 118) Controls     
Allele n F % n F % P -value P c-value OR 95%CI Allele n F % n F % P -value P c-value OR 95%CI
HLA – A*          HLA-B*         
01 26 11.0 47 9.0 ns -    07 14 5.9 38 7.3 ns -   
02 64 27.1 127 24.4 ns -    08 10 4.2 34 6.5 ns -   
03 21 8.9 56 10.8 ns -    14 10 4.2 22 4.2 ns -   
11 16 6.8 26 5.0 ns -    15 22 9.3 48 9.2 ns -   
24 24 10.2 62 11.9 ns -    18 10 4.2 36 6.9 ns -   
HLA-DRB1*          27 3 1.3 8 1.5 ns -   
01 16 6.8 42 8.1 ns     35 44 18.6 68 13.1 ns -   
03 20 8.4 61 11.7 ns -    39 8 3.4 18 3.5 ns -   
04 27 11.4 56 10.8 ns -    40 12 5.1 16 3.1 ns -   
07 29 12.3 67 12.9 ns -    44 35 14.8 46 8.9 0.0160 0.4969 1.79 1.12-2.87
08 17 7.2 30 5.8 ns -    45 0 - 12 2.3 0.0231 0.0225 - -
11 31 13.1 81 15.6 ns -    49 3 1.3 8 1.5 ns -   
13 38 16.1 54 10.4 0.0152 0.2280 1.65 1.06-2.59 51 20 8.5 44 8.5 ns -   
14 11 4.7 40 7.7 ns     52 6 2.5 11 2.1 ns -   
15 24 10.2 44 8.8 ns -            
  1. n = number of times the allele occurs; F = allele frequency; P-value = calculated by Fisher’s exact test; Pc-value = value of P corrected by Bonferroni correction; OR = odds ratio; 95%CI = 95% confidence interval; ns= not significant (p > 0.05). This table is restricted to representative allele frequencies.