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Table 4 Frequency of HLA-A, -B and –DRB1 alleles in ACL subgroup 1A and control group

From: Association between HLA genes and American cutaneous leishmaniasis in endemic regions of Southern Brazil

 

ACL (group 1A) (n = 118)

Controls (n = 260)

     

ACL (group 1A) (n = 118)

Controls

    

Allele

n

F %

n

F %

P -value

P c-value

OR

95%CI

Allele

n

F %

n

F %

P -value

P c-value

OR

95%CI

HLA – A*

        

HLA-B*

        

01

26

11.0

47

9.0

ns

-

  

07

14

5.9

38

7.3

ns

-

  

02

64

27.1

127

24.4

ns

-

  

08

10

4.2

34

6.5

ns

-

  

03

21

8.9

56

10.8

ns

-

  

14

10

4.2

22

4.2

ns

-

  

11

16

6.8

26

5.0

ns

-

  

15

22

9.3

48

9.2

ns

-

  

24

24

10.2

62

11.9

ns

-

  

18

10

4.2

36

6.9

ns

-

  

HLA-DRB1*

        

27

3

1.3

8

1.5

ns

-

  

01

16

6.8

42

8.1

ns

   

35

44

18.6

68

13.1

ns

-

  

03

20

8.4

61

11.7

ns

-

  

39

8

3.4

18

3.5

ns

-

  

04

27

11.4

56

10.8

ns

-

  

40

12

5.1

16

3.1

ns

-

  

07

29

12.3

67

12.9

ns

-

  

44

35

14.8

46

8.9

0.0160

0.4969

1.79

1.12-2.87

08

17

7.2

30

5.8

ns

-

  

45

0

-

12

2.3

0.0231

0.0225

-

-

11

31

13.1

81

15.6

ns

-

  

49

3

1.3

8

1.5

ns

-

  

13

38

16.1

54

10.4

0.0152

0.2280

1.65

1.06-2.59

51

20

8.5

44

8.5

ns

-

  

14

11

4.7

40

7.7

ns

   

52

6

2.5

11

2.1

ns

-

  

15

24

10.2

44

8.8

ns

-

           
  1. n = number of times the allele occurs; F = allele frequency; P-value = calculated by Fisher’s exact test; Pc-value = value of P corrected by Bonferroni correction; OR = odds ratio; 95%CI = 95% confidence interval; ns= not significant (p > 0.05). This table is restricted to representative allele frequencies.
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BMC Infectious Diseases

ISSN: 1471-2334

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