| |
Clearance
|
Acquisition in non-carriers
|
Acquisition in carriers
|
|---|
|
Target serotype
|
Exposure1
|
Events
|
Person-time2
|
Events
|
Person-time3
|
Events
|
Person-time4
|
|---|
|
19F
|
Yes
|
19
|
58
|
17
|
96
|
5
|
85
|
|
No
|
2
|
2
|
3
|
19
|
0
|
20
|
|
23F
|
Yes
|
10
|
23
|
10
|
47
|
2
|
54
|
|
No
|
1
|
3
|
2
|
68
|
1
|
85
|
|
6B
|
Yes
|
2
|
13
|
5
|
44
|
5
|
61
|
|
No
|
3
|
7
|
2
|
71
|
3
|
84
|
|
14
|
Yes
|
2
|
10
|
3
|
17
|
6
|
27
|
|
No
|
0
|
0
|
2
|
98
|
4
|
128
|
|
10A
|
Yes
|
2
|
11
|
1
|
27
|
1
|
44
|
|
No
|
2
|
2
|
4
|
88
|
5
|
108
|
|
19A
|
Yes
|
3
|
7
|
1
|
33
|
0
|
37
|
|
No
|
2
|
4
|
2
|
82
|
2
|
117
|
|
NT
|
Yes
|
1
|
5
|
1
|
44
|
3
|
52
|
|
No
|
1
|
6
|
1
|
71
|
3
|
102
|
|
16F
|
Yes
|
0
|
0
|
0
|
18
|
0
|
21
|
|
No
|
1
|
2
|
2
|
97
|
3
|
142
|
|
18F
|
Yes
|
1
|
1
|
1
|
4
|
0
|
7
|
|
No
|
0
|
0
|
1
|
111
|
2
|
157
|
|
11A
|
Yes
|
0
|
0
|
0
|
13
|
1
|
25
|
|
No
|
2
|
3
|
0
|
102
|
0
|
137
|
|
23B
|
Yes
|
0
|
0
|
0
|
6
|
0
|
4
|
|
No
|
1
|
1
|
1
|
109
|
0
|
160
|
|
9V
|
Yes
|
0
|
2
|
0
|
21
|
1
|
34
|
|
No
|
0
|
4
|
1
|
94
|
0
|
125
|
|
15A
|
Yes
|
0
|
0
|
0
|
4
|
0
|
7
|
|
No
|
0
|
1
|
1
|
111
|
0
|
157
|
|
8
|
Yes
|
0
|
0
|
0
|
0
|
0
|
0
|
|
No
|
0
|
0
|
0
|
115
|
1
|
165
|
|
Total:
|
Yes
|
40
|
130
|
39
|
374
|
24
|
458
|
|
No
|
15
|
35
|
22
|
1236
|
24
|
1687
|
|
55
|
165
|
78
|
1610
|
48
|
2145
|
- The crude estimates of the model parameters are (cf. Appendix): the transmission rate (per month); the community acquisition rate per serotype (in non-carrying children) (per month); the clearance rate of carriage (per month); the competition parameter . For parameter β, the denominator (60.18) is not directly readable from the data as presented in the table. Only samples available from two consecutive visits were considered, accounting for 67% of the scheduled pairs of consecutive visits. The three rooms were analysed as six rooms, separated by the summer break.
-
1 Exposure is here defined as the presence of at least one carrier of the target serotype in the other attendees in the room.
-
2 Person-time here is the total time, in months, spent carrying pneumococcus overall (total row) or a specific serotype (serotype rows) stratified by the presence or absence of other carriers of the specific serotype.
-
3 Person-time here is the total time, in months, spent as a non-carrier, stratified by exposure to the specific serotype. For the total row, the time is a sum of serotype-specific person-times.
-
4 As in 2 but for children carrying pneumococcus.
