Validation of the chronic disease score-infectious disease (CDS-ID) for the prediction of hospital-associated clostridium difficile infection (CDI) within a retrospective cohort

Table 3 Adjustment for Confounding Effects on the Association Between Antibiotic Exposure and the Risk of (CDI)

Model	Main Exposure Odds Ratio	95% CI	Change From Unadjusted Absolute (%)	c Statistic	95% CI
High Risk Antibiotics	3.21	1.42, 7.27	-	0.532	0.519, 0.546
High Risk Antibiotics + CDS-ID	2.66	1.17, 6.04	−0.55 (17)	0.658	0.623, 0.694
High Risk Antibiotics + Age	2.56	1.13, 5.84	−0.65 (20)	0.621	0.582, 0.659
High Risk Antibiotics + CDS-ID + Age	2.30	1.01, 5.23	−0.91 (28)	0.686	0.651, 0.720

Adjustment for Confounding Effects of Comorbidity and Age on the Association Between High Risk Antibiotic Exposure and the Risk of Clostridium difficile Infection (CDI).
Abbreviations: OR= Odds Ratio, CI=Confidence Interval, CDI=Clostridium difficile infection, CDS-ID =Chronic Disease Score-Infectious Disease.

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