Table 3 Comparative minimum inhibitory concentration (MIC) values of 92 clinical isolates of A. flavus on RPMI 1640 and Mueller-Hinton agar media read at 24 hours
Antifungal drug | RPMI 1640 | MH-GMB | ||||||
|---|---|---|---|---|---|---|---|---|
Range | MIC 50 | MIC 90 | Mean ± SD | Range | MIC 50 | MIC 90 | Mean ± SD | |
Amphotericin B | 0.064-4 | 0.75 | 3 | 1.129 ± 0.982 | 0.1-6 | 1 | 4 | 1.646 ± 1.529 |
Voriconazole | 0.064-0.25 | 0.125 | 0.25 | 0.153 ± 0.525 | 0.064-0.25 | 0.125 | 0.25 | 0.145 ± 0.047 |
Posaconazole | 0.016-0.38 | 0.094 | 0.25 | 0.109 ± 0.075 | 0.023-0.5 | 0.094 | 0.25 | 0.142 ± 0.109 |
Anidulafungin | 0.002-0.006 | 0.002 | 0.002 | 0.002 ± 0.000 | 0.002-0.016 | 0.002 | 0.002 | 0.00 ± 0.00 |
Micafungin | 0.002-0.008 | 0.002 | 0.002 | 0.002 ± 0.002 | 0.002-0.008 | 0.002 | 0.002 | 0.002 ± 0.001 |
Caspofungin | 0.002-0.125 | 0.008 | 0.032 | 0.016 ± 0.014 | 0.006-0.125 | 0.012 | 0.032 | 0.013 ± 0.015 |