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Table 4 Univariate clinical and demographic associations with complicated or fatal disease in 364 adults admitted to hospital with non-typhoidal Salmonella gastroenteritis who had a blood culture taken

From: A retrospective study of secondary bacteraemia in hospitalised adults with community acquired non-typhoidal Salmonella gastroenteritis

  Complicated or fatal disease Uncomplicated disease OR (95% CI) p1 Adjusted OR (95% CI) p2
Number (%) 91 (25.0) 273 (75.0)     
Age ≥ 65 years 35 (38.5) 41 (15.0) 3.54 (2.07–6.05) <0.001   
Male gender 37 (40.7) 134 (49.1) 0.71 (0.44–1.15) 0.183   
Current smoker 30 (33.0) 83 (30.4) 1.13 (0.66–1.93) 0.110   
Current alcohol user 48 (52.7) 176 (64.5) 0.06 (0.37–1.02) 0.062   
Recent travel history 14 (15.4) 35 (12.8) 1.24 (0.63–2.42) 0.595   
Chronic disease 41 (45.1) 72 (26.4) 2.29 (1.40–3.75) 0.002   
Hypochlorhydria 15 (16.5) 24 (8.8) 2.05 (1.02–4.10) 0.050   
Recent antibiotic therapy 7 (7.7) 25 (9.2) 0.83 (0.35–1.98) 0.831   
Duration symptoms > 4 days 47 (51.6) 87 (31.9) 2.28 (1.41–3.70) 0.001 2.48 (1.44–4.27) 0.001
Bloody diarrhoea 14 (15.4) 51 (18.7) 0.79 (0.42–1.51) 0.530   
Abdominal pain 69 (75.8) 215 (78.8) 0.85 (0.48–1.48) 0.561   
Vomiting 65 (71.4) 200 (73.3) 0.91 (0.54–1.55) 0.786   
Pyrexia 35 (38.5) 145 (53.1) 0.55 (0.34–0.90) 0.016 0.56 (0.32–0.95) 0.033
Rigors 14 (15.4) 69 (23.5) 0.54 (0.29–1.01) 0.060   
Headache 20 (22.0) 88 (32.2) 0.59 (0.34–1.03) 0.065   
Cough 11 (12.1) 21 (7.7) 1.65 (0.76–3.57) 0.204   
Admission temperature > 38°C 3 24 (26.4) 84 (31.1) 0.81 (0.46–1.42) 0.508   
Admission pulse > 90/min 4 46 (50.5) 105 (38.9) 1.61(1.00–2.59) 0.065   
Dehydration 67 (73.6) 148 (54.2) 2.36 (1.40–3.98) 0.001 1.90 (1.07–3.38) 0.029
Abdominal tenderness 44 (48.4) 155 (56.8) 0.71 (0.44–1.15) 0.182   
Mental impairment 18 (19.8) 9 (3.3) 7.23 (3.12–16.77) <0.001 4.80 (1.91–12.07) 0.001
Leococytosis 5 25 (27.5) 41 (15.1) 2.13 (1.21–3.77) 0.012   
Leucopenia 6 4 (4.4) 15 (5.5) 0.79 (0.26–2.44) 0.792   
Anaemia 7 9 (9.9) 20 (7.4) 1.38 (0.61–3.16) 0.503   
Elevated urea 8 46 (50.5) 67 (24.9) 3.08 (1.88–5.06) < 0.001   
Serovar Enteritidis infection 47 (51.6) 136 (49.8) 1.08 (0.65–1.78) 0.856   
Serovar Typhimurium infection 18 (19.8) 78 (28.6) 0.62 (0.33–1.14) 0.131   
Serovar Virchow infection 7 (7.7) 16 (5.9) 1.34 (0.48–3.61) 0.709   
Positive blood culture 37 (40.7) 26 (9.5) 6.51 (3.64–11.64) <0.001 5.34 (2.86–9.95) 0.001
  1. Data are number (%), except where stated.
  2. 1 Univariable comparison of patients with complicated or fatal disease compared with those with uncomplicated disease.
  3. 2 Adjusted comparison from multivariable logistic regression.
  4. 3 n = 361.
  5. 4 n = 354.
  6. 5 White blood cell count >12.0 × 109/L; n = 363.
  7. 6 White blood cell count <4.0 × 109/L; n = 363.
  8. 7 Hemoglobin <11 g/dl in females and <13 g/dl in males; n = 363.
  9. 8 Urea >7.5 mmol/l; n = 360.