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Figure 3 | BMC Infectious Diseases

Figure 3

From: Impact of antigen specificity on CD4+T cell activation in chronic HIV-1 infection

Figure 3

Antigen-specific cytokine responses detected to persistent herpes viruses and tetanus toxoid. Following a six hour stimulation, PBMCs were assessed by intracellular cytokine staining for responses to HIV, herpes viruses CMV, EBV, HSV & VZV, and the bacterial antigen tetanus toxoid. Responses were categorized according to the combination of cytokines produced (either IL-2 or IFN╬│ alone, or both together). Cytokine responses for each antigen are shown with HIV- donors on the left and HIV+ donors on the right. Unpaired 2-tailed t-tests were used to compare responses between HIV+ and HIV- donors.

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