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Table 3 The genotype frequencies of Arg587Arg (CGT → CGG) SNP of NOD2 gene in patients and controls of Chinese Han, Uyghur and Kazak populations

From: A novel single nucleotide polymorphism within the NOD2 gene is associated with pulmonary tuberculosis in the Chinese Han, Uygur and Kazak populations

 

Genotype

Patients

Controls

Trend P-value

OR

(95%CI)

  

N(Freq)

N(Freq)

  

Han

T/T

162(0.74)

185(0.86)

 

1.00

 

T/G

53(0.242)

28(0.13)

0.0023

2.16(1.31-3.58)

 

G/G

4(0.018)

2(0.009)

 

2.28(0.41-12.63)

Uygur

T/T

49(0.57)

37(0.514)

 

1.00

 

T/G

29(0.337)

29(0.403)

0.6575

0.76(0.39-1.47)

 

G/G

8(0.093)

6(0.083)

 

1.01(0.32-3.15)

Kazak

T/T

65(0.542)

56(0.602)

 

1.00

 

T/G

47(0.392)

32(0.344)

0.3838

1.27(0.71-2.25)

 

G/G

8(0.067)

5(0.054)

 

1.38(0.43-4.46)

  1. Genotype frequencies were compared between the patients and control subjects by Armitage Trend test and χ 2 test. N = number of alleles; Freq = frequency; CI = confidence interval; OR = odds ratio.