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Table 3 Results of 2009 pandemic influenza A (H1N1) antibodies before and after the pandemic in 60 vaccinated and 90 unvaccinated health care workers at a children's hospital in Taiwan

From: Longitudinal seroepidemiologic study of the 2009 pandemic influenza A (H1N1) infection among health care workers in a children's hospital

 

All (N = 150)

Vaccinated (N = 60)

No. (%)

Unvaccinated (N = 90)

   

All

No. (%)

High-risk (N = 40)3

No. (%)

Low-risk (N = 50)3

No. (%)

P value1

Seroprotective

      

Baseline2

7 (4.7%)

2 (3.3%)

5 (5.6%)

3 (7.5%)

2 (4.0%)

0.652

Second2

13 (8.7%)

2 (3.3%)

11 (12.2%)

8 (20.0%)

3 (6.0%)

0.056

Third2

52 (35.4%)

34 (56.7%)

18 (20.0%)

12 (30.0%)

6(12.0%)

0.061

Seroconversion

      

1st to 2nd sera

6 (4.0%)

0 (0.0%)

6 (6.7%)

5 (12.5%)

1 (2.0%)

0.085

2nd to 3 rd sera

39 (26.5%)

32 (53%)

7 (7.8%)

4 (10.0%)

3 (6.0%)

0.695

1st to 3 rd sera

45 (30.6%)

32 (53%)

13 (14.4%)

9 (22.5%)

4 (8.0%)

0.071

GMT (95% CI)

      

Base line

11.0 (10.7-12.0%)

11.0 (10.5-12.6)

11.2 (10.4-12.1)

12.1 (10.5-13.9)

10.6 (9.7-11.5)

0.049

Second

12.4 (11.4-13.6%)

11.4 (10.4-12.4)

13.2 (11.5-15.1)

16.0 (12.6-20.3)

11.3 (9.9-12.9)

0.013

Third

19.2 (16.6-22.1%)

31.4 (23.8-36.8)

14.0 (12.0-16.3)

18.3 (14.0-24.1)

11.3 (9.8-13.1)

0.003

  1. Abbreviations: GMT: geometric mean titer; CI: confidence interval.
  2. 1 Comparisons were made between high- and normal-risk groups, using Chi-square or Fisher exact tests.
  3. 2 See text and Figure 2 for definitions of baseline, second, and third samples.
  4. 3 See text for definitions of high- and low-risk.
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BMC Infectious Diseases

ISSN: 1471-2334

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