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Table 2 History of acute respiratory illness, including influenza-like illness (ILI), and laboratory evidence of 2009 pandemic influenza A (H1N1) infections in 60 vaccinated with a monovalent 2009 pandemic influenza A(H1N1) vaccine and 90 unvaccinated healthcare workers at a children's hospital during and after 2009 acute H1N1 influenza pandemic in Taiwan

From: Longitudinal seroepidemiologic study of the 2009 pandemic influenza A (H1N1) infection among health care workers in a children's hospital

 

All

(N = 150)

Vaccinated

Unvaccinated

 
  

All (N = 60)

No. (%)

High risk1 (N = 53)

No. (%)

Low risk1 (N = 7)

No. (%)

P value2

All (N = 90)

No. (%)

High risk1 (N = 40)

No. (%)

Low risk1 (N = 50)

No. (%)

P value2

Age, mean ± SD [range], year

31.8 ± 6.3[22-59]

31.7 ± 5.8[24-59]

31.8 ± 5.8[27-59]

31.1 ± 6.2[24-42]

0.534

31.8 ± 6.7[23-58]

29.5 ± 5.5[23-58]

33.9 ± 6.9[23-51]

< 0.001

Male: Female

34:116

16:44

16:37

0:7

0.173

18:72

12:28

6:44

0.061

History of respiratory illness

         

Before 1st serum

         

Acute respiratory illness

23 (15.3%)

16 (26.7%)

11 (20.8%)

5 (71.4%)

0.012

7 (7.8%)

3 (7.5%)

4 (8.0%)

1

ILI episodes

9 (6.0%)

5 (8.3%)

3 (5.7%)

2 (28.6%)

0.100

4 (4.4%)

2 (5.0%)

2 (4.0%)

1

2009 H1N1 infection3

0(0%)

0(0%)

0(0%)

0(0%)

NA

0 (0%)

0 (0%)

0 (0%)

NA

Between 1st & 2nd sera

         

Acute respiratory illness

54 (36%)

21 (35.0%)

18 (34.0%)

3 (42.9%)

0.687

33 (36.7%)

15 (37.5%)

18 (36.0%)

1

ILI episode

13 (8.7%)

5 (8.3%)

5 (9.4%)

0(0%)

1

8 (8.9%)

6 (15.0%)

2 (4.0%)

0.132

2009 H1N1 infection3

8 (5.3%)

1 (1.7%)

1 (1.9%)

0(0%)

1

7 (7.8%)

5 (12.5%)

2 (4.0%)

0.235

Virologically confirmed4

5 (3.3%)

1 (1.7%)

1 (1.9%)

0(%))

1

4 (4.4%)

3 (7.5%)

1 (2.0%)

0.319

With serological evidence5

6 (4.0%)

0(0%)

0(0%)

0(0%)

1

6 (6.7%)

5 (12.5%)

1 (2.0%)

0.085

Between 2nd & 3rd sera

         

Acute respiratory illness

57 (38%)

24 (40.0%)

21 (39.6%)

3 (42.9%)

1

33 (36.7%)

15 (37.5%)

18 (36.0%)

1

ILI episodes

23 (15.3%)

10 (16.6%)

9 (17.0%)

1 (14.3%)

1

13 (14.4%)

7 (17.5%)

6 (12.0%)

0.552

2009 H1N1 infection3

10 (6.7%)

2 (3.3%)

2 (3.8%)

0 (0%)

1

8 (8.9%)

5 (12.5%)

3 (6.0%)

0.458

Virologically confirmed4

6 (4.0%)

2 (3.3%)

2 (3.8%)

0 (0%)

1

4 (4.4%)

2 (5.0%)

2 (4.0%)

1

With serological evidence5

7 (4.7%)

NA

NA

NA

NA

7 (7.8%)

4 (10.0%)

3 (6.0%)

0.695

  1. Abbreviations: NA, not applicable; SD, standard deviation; ILI, influenza-like illness
  2. 1 See text for definition of high- and low-risk groups
  3. 2 P values were calculated by Chi-square test or Fisher exact test to compare high- and low-risk groups.
  4. 3 2009 H1N1 infection means subjects with laboratory evidence, either positive viral isolation, positive real time polymerase chain reaction, or seroconversion, of 2009 pandemic influenza A (H1N1) infection.
  5. 4 Virologically confirmed means either viral isolation or real-time polymerase chain reaction was positive of 2009 pandemic influenza (H1N1) virus.
  6. 5 With serological evidence with seroconversion or four fold rise of antibodies against 2009 pandemic influenza (H1N1) virus.
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BMC Infectious Diseases

ISSN: 1471-2334

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