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Table 2 Diagnostic performance of Inno-Lia algorithms for recent HIV-1 infection among the 1267 patients with incident or older infection of Table 1

From: Diagnostic performance of line-immunoassay based algorithms for incident HIV-1 infection

Alg
#
Definition Sensitivity
%
Specificity
%
Overall correct %
(rank)
LLR Chi-square
(rank)
Rank sum
(final rank)
15.1 if (sgp120 ≤ 1 AND p31 ≤ 1 AND p17 ≤ p24)
OR (gp41 ≤ 2 AND p31 ≤ 1 AND p17 ≤ p24)
OR (p17 ≥ 2 AND p31 = 0 AND p17 ≤ p24)
OR (p31 = 0 AND p24 ≥ 2 AND p17 ≤ p24)
then RECENT
else older
61.67 95.14 81.22
(1)
524.69
(2)
3
(1)
15 if (sgp120 ≤ 1 AND p31 ≤ 1)
OR (gp41 ≤ 2 AND p31 ≤ 1)
OR (p17 ≥ 2 AND p31 = 0)
OR (p31 = 0 AND p24 ≥ 2)
then RECENT
else older
62.24 94.32 80.98
(2)
509.19
(4)
6
(2)
11.2 if (sgp120+gp41 ≤ 2.5)
OR ((sgp120+gp41+p31+p24+p17 ≤ 6.5) AND p31 ≤ 1 AND p17 ≤ p24)
OR (p31 = 0 AND p24 ≥ 2)
then RECENT
else older
61.48 94.05 80.51
(3)
490.62
(6)
9
(3.5)
13 if (sgp120+gp41 ≤ 4 AND p31 = 0)
OR (p31 = 0 AND p24 ≥ 2)
then RECENT
else older
59.77 95.00 80.35
(4)
493.18
(5)
9
(3.5)
7 if sgp120+gp41+p31 ≤ 4
then RECENT
else older
54.08 98.38 79.95
(10.5)
530.11
(1)
11.5
(5)
9 if sgp120+gp41 ≤ 4 AND p31 = 0
then RECENT
else older
52.75 98.38 79.40
(12)
511.40
(3)
15
(6)
11.1 if (sgp120+gp41 ≤ 2.5)
OR ((sgp120+gp41+p31+p24+p17 ≤ 6.5) AND p31 ≤ 1
OR (p31 = 0 AND p24 ≥ 2)
then RECENT
else older
61.48 93.51 80.19
(6.5)
475.99
(9)
15.5
(7)
12.1 if (p24 ≥ 2 AND p31 = 0)
OR (gp41 ≤ .5)
OR (sgp120+gp41+p31 ≤ 4)
OR (p31 ≤ 1 AND (sgp120+gp41+p31+p24+p17 ≤ 6.5))
then RECENT
else older
61.67 93.38 80.19
(6.5)
475.12
(10)
16.5
(8)
4.1 if p31 ≤ 0.5
then RECENT
else older
63.95 91.89 80.27
(5)
470.01
(14)
19
(9.5)
12 if (p24 ≥ 2 AND p31 = 0)
OR (gp41 ≤ .5)
OR (sgp120+gp41+p31 ≤ 4
OR sgp120+gp41+p31+p24+p17 ≤ 6.5)
then RECENT
else older
61.67 93.37 80.17
(8)
474.55
(11)
19
(9.5)
8.1 if gp41 ≤ 0.5
OR (sgp120+gp41+p31 ≤ 4)
OR ((sgp120+gp41+p31+p24+p17 ≤ 6.5) AND p31 ≤ 1)
then RECENT
else older
54.65 96.76 79.24
(13)
476.63
(7)
20
(11)
11 if (sgp120+gp41 ≤ 2.5)
OR (sgp120+gp41+p31+p24+p17 ≤ 6.5)
OR (p31 = 0 AND p24 ≥ 2)
then RECENT
else older
61.48 93.37 80.09
(9)
471.87
(12)
21
(12)
8 if gp41 ≤ 0.5
OR (sgp120+gp41+p31 ≤ 4)
OR (sgp120+gp41+p31+p24+p17 ≤ 6.5)
then RECENT
else older
54.65 96.75 79.23
(14)
476.13
(8)
22
(13)
13.1 if gp41 ≤ 2
OR (p31 = 0 AND p24 ≥ 2)
then recent
else older
60.34 93.92 79.95
(10.5)
470.77
(13)
23.5
(14)
3 if gp41 ≤ 0.5
then RECENT
else older
20.30 100.0 66.85
(25)
201.79
(23)
24.5
(22)
4 if p31 = 0
then RECENT
else older
60.15 92.70 79.16
(15)
436.83
(16)
31
(15)
17 if (sgp120 * gp41) ≤ 2
then RECENT
else older
50.09 98.24 78.22
(17)
469.33
(15)
32
(16)
2 if sgp120 ≤ 1
then RECENT
else older
54.46 95.41 78.37
(16)
431.97
(17)
33
(17)
16 if (sgp120 ≤ 1 AND (p31+p24+p17 ≤ 2.5))
OR (gp41 ≤ 1)
OR (p31 ≤ 0.5 AND (sgp120+gp41+p24+p17 ≥ 15))
OR (p24 = 0 AND gp41 ≤ 2)
OR (p24 ≥ 3 AND p31 = 0)
then RECENT
else older
50.47 96.62 77.43
(18)
416.47
(19)
37
(18.5)
18 if (sgp120 * gp41 ≤ 1)
OR (p24+p31 = 0)
then RECENT
else older
46.11 98.24 76.56
(19)
416.96
(18)
37
(18.5)
14 if (sgp120+gp41+p31+p24+p17 ≤ 6.5 AND p31 ≤ 1)
then RECENT
else older
45.92 97.84 76.24
(20)
399.26
(20)
40
(20)
3.2 if gp41 ≤ 2
then RECENT
else older
44.02 98.11 75.61
(21)
385.38
(21)
42
(21)
6 if p17 = 0
then RECENT
else older
40.80 90.80 69.98
(22)
178.75
(24)
46
(22.5)
3.1 if gp41 ≤ 1
then RECENT
else older
23.53 100.0 68.19
(24)
236.77
(22)
46
(22.5)
10 if p31 = 0 AND p24 ≥ 2
then RECENT
else older
30.93 95.27 68.51
(23)
164.49
(25)
48
(24.5)
5 if p24 ≤ 0
then RECENT
else older
26.00 95.54 66.61
(26)
125.29
(26)
52
(26)
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