Figure 1

Representative confocal microendoscopy and histology images. For each treatment group, a 3 × 3 layout of 9 confocal images representing positions 1,3,5,11,13,15,21,23,25 of the sampled 5 × 5 image matrix from a single animal is shown (left column), followed by a single larger confocal image (center column), and corresponding H&E section (right column). (a) 5 × 5 matrix representing the positions of the 25 imaged sites per animal. (b-d) representative PBS case; (e-g) representative HEC treated case, (h-j) representative 0.02% BZK treated case; (k-m) representative 0.2% BZK treated case; (n-p) representative N-9 treated case. Confocal images are shown in pseudocolor for ease of visualization with the intensity represented by the shown color (black represents a zero intensity value, progressing to yellow for maximum intensity). Scale bar 100 μm.