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Table 3 Univariate and multivariate analysis of clinical variables associated with invasive fungal infection

From: Invasive fungal infection among hematopoietic stem cell transplantation patients with mechanical ventilation in the intensive care unit

  Univariate analysis Multi-variate analysis
Variable Odds Ratio 95% C.I. P-value Odds ratio 95% C.I. P-value
Age > 30 0.333 0.108 - 1.034 0.053        
Gender 0.900 0.300 - 2.704 0.099        
Late ICU admission (> 40 days after HSCT) 6.500 1.916 - 22.052 0.002 ** 1.003 1.001 - 1.006 0.008 *
Type of transplantation 0.465 0.114 - 1.906 0.281        
GVHD 6.667 1.874 - 23.714 0.002 * 8.291 1.687 - 40.746 0.009 *
CMV infection 3.051 0.862 - 10.799 0.101        
Neutropenia (ICU admission) 1.000 0.261 - 3.826 0.099        
Concurrent bacteremia 0.808 0.267 - 2.440 0.705        
High dose corticosteroid use 5.571 1.738 - 17.856 0.003 * 9.459 2.040 - 43.867 0.004 *
APACHE II > 25 0.130 0.033 - 0.518 0.002 *       
SOFA > 12 0.250 0.071 - 0.880 0.025 *       
ICU Mortality 0.810 0.173 - 3.792 0.676        
  1. a. If cells had expected count less than 5, Fisher's Exact Test was used.
  2. b. *: p < 0.05; **: p < 0.01
  3. Abbreviations: C.I.: confidence interval; HSCT: hematopoietic stem cell transplantation; GVHD: graft versus host disease; CMV: cytomegalovirus; APACHE II: acute physiology and chronic health evaluation II; SOFA score: sequential organ failure assessment score; ICU: intensive care unit.