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Table 6 Bivariate analyse of factors predictive of sustained virologic response (SVR)

From: The effectiveness of retreatment with peginterferon alfa and ribavirin in patients with chronic viral hepatitis C genotype 2 and 3: a prospective cohort study in Brazil

Parameter n SVR Failure SVR p*
  216 n = 88 n = 128  
Age (yrs) (mean ± SD)**   51.3 ± 9.7 55.2 ± 8.2 0.002
Gender 216    
  Male 123 50 (40.7%) 73 (59.3%) 1.000
  Female 93 38 (40.9%) 55 (59.1%)  
BMI (Kg/m2) 143    
  < 30 104 41 (39.4%) 63 (60.6%) 0.591
  ≥ 30 39 18 (46.2%) 21 (53.8%)  
Median Aminotrasferase levels, (U/L)*** 215 n = 88 n = 127  
  ALT   93 ± 108 97 ± 110 0.144
Histological diagnosis**** 196    
  Fibrosis stage 0 – 2 47 29 (61.7%) 18 (38.3%) 0.001
  Fibrosis stage 3 – 4 149 48 (32.2%) 101(67.8%)  
Baseline serum HCV RNA (IU/mL)***** 155    
  < 800.000 55 25 (45.5%) 30 (54.5%) 0.714
  ≥ 800.000 100 41 (41.0%) 59 (59%)  
  1. * Significance based on qui-quadrado de Pearson test, t-student and Mann–Whitney.
  2. **Mean ± standard deviation.
  3. ***Median (interquartile range).
  4. ****Twenty missing (9.3%).
  5. *****Sixty-eight missing (31.5%).
  6. *****Sixty-one missing (28,2%).