The effectiveness of retreatment with peginterferon alfa and ribavirin in patients with chronic viral hepatitis C genotype 2 and 3: a prospective cohort study in Brazil

Table 6 Bivariate analyse of factors predictive of sustained virologic response (SVR)

Parameter	n	SVR	Failure SVR	p*
	216	n = 88	n = 128
Age (yrs) (mean ± SD)**		51.3 ± 9.7	55.2 ± 8.2	0.002
Gender	216
Male	123	50 (40.7%)	73 (59.3%)	1.000
Female	93	38 (40.9%)	55 (59.1%)
BMI (Kg/m2)	143
< 30	104	41 (39.4%)	63 (60.6%)	0.591
≥ 30	39	18 (46.2%)	21 (53.8%)
Median Aminotrasferase levels, (U/L)***	215	n = 88	n = 127
ALT		93 ± 108	97 ± 110	0.144
Histological diagnosis****	196
Fibrosis stage 0 – 2	47	29 (61.7%)	18 (38.3%)	0.001
Fibrosis stage 3 – 4	149	48 (32.2%)	101(67.8%)
Baseline serum HCV RNA (IU/mL)*****	155
< 800.000	55	25 (45.5%)	30 (54.5%)	0.714
≥ 800.000	100	41 (41.0%)	59 (59%)

* Significance based on qui-quadrado de Pearson test, t-student and Mann–Whitney.
**Mean ± standard deviation.
***Median (interquartile range).
****Twenty missing (9.3%).
*****Sixty-eight missing (31.5%).
*****Sixty-one missing (28,2%).

ISSN: 1471-2334