|
Antimicrobial agents
|
MIC range, μg/mL
|
MIC
50,
μg/mL
|
MIC
90,
μg/mL
|
Susceptible percentage,%
|
P-value
|
|---|
|
RNKP(n = 48)
|
RPKP(n = 36)
|
RNKP
|
RPKP
|
RNKP
|
RPKP
|
all isolates
|
RNKP
|
RPKP
|
|---|
|
Imipenem
|
4-256
|
8-128
|
128
|
128
|
256
|
128
|
0
|
0
|
0
|
—
|
|
Meropenem
|
2-256
|
4-128
|
64
|
64
|
128
|
64
|
0
|
0
|
0
|
—
|
|
Ertapenem
|
4-512
|
8-512
|
128
|
128
|
256
|
128
|
0
|
0
|
0
|
—
|
|
Cefotaxime
|
16 to >512
|
16 to >512
|
256
|
>512
|
512
|
>512
|
0
|
0
|
0
|
—
|
|
Cefepime
|
4-256
|
4-512
|
128
|
128
|
128
|
512
|
11.1
|
11.1
|
11.1
|
>0.99
|
|
Gentamicin
|
1 < to >512
|
256 to >512
|
8
|
>512
|
128
|
>512
|
21
|
47.2
|
0
|
<0.01
|
|
Netilmicin
|
1 to >512
|
256 to >512
|
8
|
>512
|
256
|
>512
|
32.1
|
72.2
|
0
|
<0.01
|
|
Amikacin
|
2 to >512
|
256 to >512
|
4
|
>512
|
>512
|
>512
|
39.5
|
88.9
|
0
|
<0.01
|
|
Tetracycline
|
4 to >512
|
8-256
|
16
|
32
|
512
|
128
|
3.7
|
8.3
|
0
|
0.084
|
|
Minocycline
|
2-128
|
4-32
|
4
|
8
|
64
|
32
|
27.2
|
52.8
|
6.7
|
<0.01
|
|
Ciprofloxacin
|
0.25 < to 64
|
2-64
|
64
|
64
|
64
|
64
|
6
|
13.9
|
0
|
0.015
|
|
Ofloxacin
|
0.25 < to 64
|
1-64
|
64
|
64
|
64
|
64
|
8.4
|
13.9
|
4.3
|
0.23
|
|
Tigecycline
|
0.5-4
|
0.5-4
|
2
|
2
|
2
|
2
|
96.3
|
97.2
|
95.6
|
>0.99
|
|
Colistin
|
0.25-256
|
0.5-2
|
1
|
1
|
2
|
2
|
98.8
|
97.2
|
100
|
0.44
|
|
Fosfomycin
|
1 to >1024
|
2 to > 1024
|
16
|
>1024
|
64
|
>1024
|
43.4
|
88.9
|
8.5
|
<0.01
|
- Footnotes. RPKP, rmtB-positive KPC-producing K. pneumoniae; RNKP, rmtB-negative KPC-producing K. pneumoniae; MIC, minimum inhibitory concentration; MIC50, MIC required to inhibit the growth of 50% of organisms; MIC90, MIC required to inhibit the growth of 90% of organisms.
