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Table 1 Microbiological characteristics of the 35 representative CIP-R E. coli; phylogroups, MLST STs (clonal complexes; Cplx), presence/absence of the aac (6’)-1b-cr variant and beta-lactamase content

From: Ciprofloxacin-resistant Escherichia coli in Central Greece: mechanisms of resistance and molecular identification

Strain ID Isolation date Antimicrobial resistant pattern ESBL Phylogroup/ MLST ST (CC) aac (6’)-Ib-cr beta-lactamase content
GyrA:S83L + D87N/ ParC: S80I + E84V (n = 21)
347 13/6/2011 AM,AMC,CAZ,CTX,ATM,GM,NN,TE,SXT,CIP, NOR positive B2/ ST131 ( − ) CTX-M-15
161 27/5/2011 AM,AMC,CAZ,CTX,ATM, NN,TE,SXT,CIP NOR positive B2/ ST131 ( + ) CTX-M-15 + OXA-1
391 30/5/2011 AM,AMC,CAZ,CTX,ATM,GM,NN,TE,SXT,CIP,NOR positive B2/ ST131 ( + ) CTX-M-15 + OXA-1
392 9/6/2011 AM,AMC,CAZ,CTX,ATM,GM,NN,TE,SXT,CIP,NOR positive B2/ ST131 ( + ) CTX-M-15 + OXA-1
393 18/7/2011 AM,AMC,CAZ,CTX,ATM,GM,NN,TE,SXT,CIP,NOR positive B2/ ST131 ( + ) CTX-M-15 + OXA-1
399 2/8/2011 AM,AMC,CAZ,CTX,ATM,GM,NN,TE,SXT,CIP,NOR positive B2/ ST131 ( + ) CTX-M-15 + OXA-1
160 3/5/2011 AM,AMC,CAZ,CTX,ATM,SXT,CIP,NOR positive B2/ ST131 ( + ) CTXM-15 + TEM-1
505 4/9/2011 AM,AMC,CAZ,CTX,ATM,AN,GM,NN,SXT,CIP,NOR positive B2/ ST131 ( + ) CTX-M-15 + TEM-1 + OXA-1
397 4/8/2011 AM,AMC,CAZ,CTX,ATM,TE, SXT, CIP, NOR positive B2/ ST131 ( − ) CTX-M-3
270 1/5/2011 AM,AMC,NN,SXT,CIP,NOR negative B2/ ST131 ( + ) OXA-1
301 5/5/2011 AM, AMC,NN,TE,CIP,NOR negative B2/ ST131 ( + ) OXA-1
307 6/6/2011 AM,AMC, GM, NN, TE,CIP, NOR negative B2/ ST131 ( + ) OXA-1
252 1/5/2011 AM, SXT,CIP,NOR negative B2/ ST131 ( − ) TEM-1
206 16/5/2011 AM,AMC,GM,TE,SXT,CIP,NOR negative B2/ ST131 ( + ) TEM-1 + OXA-1
320 25/5/2011 AM,AMC,CIP,NOR negative B2/ ST131 ( + ) TEM-1 + OXA-1
346 3/6/2011 AM,AMC,AN,GM,NN,SXT,TE,CIP,NOR negative B2/ ST131 ( + ) TEM-1 + OXA-1
803 4/12/2011 AM,AMC,CAZ,CTX, IMP,MEM,CIP, NOR negative B2/ ST131 ( + ) VIM-1-like + TEM-1+ OXA-1
220 5/5/2011 TE, SXT,CIP,NOR negative B2/ ST131 ( − ) none
321 18/7/2011 CIP,NOR negative B2/ ST131 ( − ) none
354 1/7/2011 TE,CIP,NOR negative B2/ ST131 ( − ) none
355 15/8/2011 TE,SXT,CIP,NOR negative B2/ ST131 ( − ) none
GyrA:S83L + D87N/ ParC: S80I + E84G (n = 1)
296 6/8/2011 AM, TE, CIP, NOR negative D/ ST393 (ST31 Cplx) ( + ) TEM-1
Strain ID Isolation date Antimicrobial susceptibility pattern ESBL Phylogroup/MLST ST (CC) aac (6’)-Ib-cr beta-lactamase content
GyrA:S83L + D87N/ ParC: S80I (n = 13)
148 9/6/2011 AM,AMC,CAZ,CTX,ATM,IMP,MEM,NN,SXT,CIP,NOR positive B2/ ST410 ( + ) KPC-2 + CTXM-15 + TEM-1 + OXA-1
(ST23 Cplx)
182 17/5/2011 AM,AMC,CAZ,CTX,ATM,IMP,MEM,AN,NN,TE,CIP,NOR positive B2/ ST410 ( + ) KPC-2 + CTXM-3 + TEM-1+ OXA-1
(ST23 Cplx)
252 10/6/2011 AM,AMC,CAZ,CTX,ATM,IMP,MEM,NN,TE,CIP,NOR positive B2/ ST410 ( + ) KPC-2 + CTXM-3 + TEM-1 + OXA-1
(ST23 Cplx)
648 31/12/2011 AM,AMC,CAZ,CTX,IMP,MEM,NN,TE,CIP,NOR negative B2/ ST410 ( − ) KPC-2 + TEM-1
(ST23 Cplx)
132 24/5/2011 AM,AMC,CAZ,CTX,ATM,AN,NN,TE,SXT,CIP,NOR positive B2/ ST410 ( + ) CTXM-15 + TEM-1 + OXA-1
(ST23 Cplx)
281 15/8/2011 AM,AMC,CAZ,CTX,ATM,AN,GM,NN,TE,SXT,CIP,NOR positive B2/ ST410 ( + ) CTXM-15 + OXA-1
(ST23 Cplx)
384 30/11/2011 AM,AMC,CAZ,CTX,ATM,AN,TE,SXT,CIP,NOR positive B2/ ST44 ( + ) CTXM-15
(ST10 Cplx)
383 22/9/2011 AM,TE,SXT,CIP,NOR negative A/ ST90 ( + ) TEM-1
(ST23 Cplx)
259 14/7/2011 AM,TE,SXT,CIP,NOR negative B1/ ST162 ( + ) TEM-1
(ST469 Cplx)
328 10/9/2011 AM,SXT,CIP,NOR negative B2/ ST361 ( − ) TEM-1
362 21/10/2011 AM,TE,SXT,CIP,NOR negative D/ ST393 ( − ) TEM-1
(ST31 Cplx)
129 25/5/2011 AM,TE,SXT,CIP,NOR negative B2/ ST1140 ( − ) TEM-1
327 9/6/2011 CIP, NOR negative A/ ST2509 ( − ) none