Anti TB-drugs | Number of resistant isolates | Patterns of gene mutations (wild-type/mutant) | Amino acid Changes | Frequency (n) |
---|---|---|---|---|
Isoniazid | 35 | katGWT/katGMUT1 | Ser315Thr1 | 33 |
 |  | inhA WT1/inhA MUT1 | C15T | 2 |
Rifampicin | 15 | rpoB WT8/rpoB MUT3 | Ser531Leu | 11 |
 |  | rpoB WT7/rpoB MUT2B | His526Asp | 1 |
 |  | rpoB WT2 &3/NA | Unknown | 1 |
 |  | rpoB WT4/ND | Unknown | 1 |
 |  | rpoB WT6/NA | Unknown | 1 |
Ethambutol | 8 | embB WT/embB MUT1A | Met306Ile | 2 |
 |  | embB WT/embB MUT1B | Met306Val | 1 |
 |  | embB WT/ND | Unknown | 5 |