Unexposed, age-matched individuals | |||||||
---|---|---|---|---|---|---|---|
TSpot positive n=13 | TSpot negative n=136 | Odds ratio | Univariate P | ||||
n | % | n | % | ||||
Age (years), median (range) | 64 | (45-87) | 70 | (25-93) | 0.81 | ||
Male, n (%) | 5 | (38) | 70 | (52) | 0.36 | ||
Ethnicity, n (%) | |||||||
White Caucasian | 13 | (100) | 136 | (100) | |||
Country of birth | |||||||
UK born | 9 | (69) | 126 | (93) | 0.18 | 0.006 | |
Other | 4 | (31)† | 10 | (7.4) | |||
Years since immigration, median (range) | 43 | (21-62) | 52 | (8-61) | |||
Ever visited a high prevalence country, n (%) | 4 | (31) | 47 | (35) | 0.84 | ||
Years since last visit, median (range) | 8.5 | (0-40) | 5.5 | (0-60) | |||
Ever resident in a high prevalence area >6/52, n (%) | 2 | (15) | 27 | (20) | 0.64 | ||
Occupation: healthcare, prison, lab n (%)‡ | 4 | (31) | 18 | (13) | 0.09 | ||
BCG (history or scar), n (%) | |||||||
Yes | 7 | (54) | 66 | (49) | 0.73 | ||
No | 4 | (31) | 44 | (33) | |||
Unknown | 2 | (15) | 26 | (19) | |||
Medical history, n (%) | |||||||
Comorbidity known to be associated with TB§ | 0 | (0) | 21 | (16) | 0.22 | ||
Immunosuppresive medications∥ | 4 | (31) | 12 | (9.2) | 4.6 | 0.015 | |
Ever known to be exposed to TB | 4 | (31) | 26 | (19) | 0.32 | ||
Ever had treatment for tuberculosis | 2 | (15) | 2 | (1.5) | 12 | 0.003 |