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Table 3 Risk of low-grade squamous intraepithelial neoplasia (LSIL) diagnosis at each visit given vaginal pH measurement, stratified by age at visit

From: A large, population-based study of age-related associations between vaginal pH and human papillomavirus infection

Vaginal pH Level N Percent with LSIL Odds of LSIL Cytologya (95% CI) p-value
All Womenb     
4.0-4.5 19,272 2.4 ref < 0.01
5.0-5.5 9,059 2.5 1.3 (1.1-1.6)  
Age at Visit     
< 25 years     
4.0-4.5 1,536 4.0 ref 0.12
5.0-5.5 475 5.7 1.5 (0.9-2.3)  
25-34 years     
4.0-4.5 6,178 2.9 ref 0.02
5.0-5.5 1,721 4.0 1.4 (1.0-1.9)  
35-44 years     
4.0-4.5 6,074 2.3 ref 0.30
5.0-5.5 1,568 2.8 1.2 (0.9-1.7)  
45-54 years     
4.0-4.5 3,216 1.9 ref 0.33
5.0-5.5 1,776 2.3 1.2 (0.8-1.8)  
55-64 years     
4.0-4.5 1,308 1.3 ref 0.82
5.0-5.5 1,653 1.4 1.1 (0.6-1.9)  
65+ years     
4.0-4.5 960 0.5 ref 0.04
5.0-5.5 1,866 1.4 2.7 (1.0-7.0)  
  1. a Generalized estimating equation models with an independent correlation structure were used to estimate the odds of testing positive LSIL given dichotomous pH measurements at each visit
  2. b Adjusted for age at visit