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Table 2 Meningococcal meningitis among children aged < 60 months in China, Korea and Vietnam by age and gender group, 1999 through 2002*

From: An expanded age range for meningococcal meningitis: molecular diagnostic evidence from population-based surveillance in Asia

Characteristics

PCR-confirmed

Culture-confirmed

Total

China

Korea

Vietnam

Vietnam

(n = 56)

(n = 92)

(n = 110)

(n = 10)

(n = 268)b

N (%)

N (%)

N (%)

N (%)

N (%)

Age (months)

 < 1

17 (30.4)

28 (30.4)

23 (20.9)

1 (10.0)

69 (25.7)

 1-6

11 (19.6)

26 (28.3)

29 (26.4)

1 (10.0)

67 (25.0)

 7-11

5 (8.9)

4 (4.3)

21 (19.1)

4 (40.0)

34 (12.7)

 12-23

11 (19.6)

11 (12.0)

9 (8.2)

3 (30.0)

34 (12.7)

 24-35

3 (5.4)

4 (4.3)

8 (7.3)

1 (10.0)

16 (6.0)

 36-47

6 (10.7)

11 (12.0)

11 (10.0)

0

28 (10.4)

 48-59

3 (5.4)

8 (8.7)

9 (8.2)

0

20 (7.5)

Gender

 Female

13 (23.2)

31 (33.7)

53 (48.2)

5 (50.0)

102 (38.1)

 Male

43 (76.8)

61 (66.3)

57 (51.8)

5 (50.0)

166 (61.9)

Clinical features

 Lethargy/coma

19 (33.9)

8 (8.7)

60 (54.5)

4 (40.0)

91 (34.0)

 Irritability/confusion

17 (30.4)

7 (7.6)

29 (26.4)

4 (40.0)

57 (21.3)

 Nuchal rigidity

17 (30.4)

7 (7.6)

43 (39.1)

6 (60.0)

71 (26.5)

 Seizure

30 (53.6)

13 (14.1)

51 (46.4)

4 (40.0)

98 (36.6)

 Vomiting

3 (5.4)

18 (19.6)

64 (58.2)

7 (70.0)

92 (34.3)

 Bulging fontanelle

8 (14.3)

1 (1.1)

31 (28.2)

2 (20.0)

42 (15.7)

 Fever or septic appearance

29 (51.8)

80 (87.0)

82 (74.5)

9 (90.0)

200 (74.6)

Outcome

 Alive

53 (94.6)

UK

UK

8 (80.0)

NA

 Deceased

3 (5.4)

UK

UK

2 (20.0)

NA

Prior antibiotic usage

 Yes

23 (41.1)

53 (57.6)

78 (70.9)

10 (100.0)

164 (61.2)

  1. aSurveillance periods: China, January 1, 2000--December 31, 2002; South Korea: September 1, 1999--December 31, 2001; Vietnam: March 4, 2000-March 3, 2002.
  2. b26 specimens (China, n = 11; Vietnam, n = 15) could not be linked with the clinical database were excluded from analysis.