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Table 1 Characteristics on admission of K. pneumoniae infected patients compared to patients with H. influenzae/S pneumoniae ALRI aged ≥5 years in univariate analysis

From: Klebsiella pneumoniaerelated community-acquired acute lower respiratory infections in Cambodia: Clinical characteristics and treatment

 

Patients with K. pneumoniaeALRI

(n = 43)

Patients with H. influenzaeand S. pneumoniaeALRI

(n = 160)

P-value

Age, median years (Inter Quartile Range [IQR])

55 (45-72)

57 (42-65)

0.8

Male gender (%)

14 (32.6)

80 (50.0)

0.04

Co-morbidities (%)

   

   Smoking history

10 (23.3)

50 (31.2)

0.3

   Cardiovascular disease

6 (13.9)

17 (10.6)

0.5

   Diabetes mellitus

7 (16.3)

10 (6.2)

0.03

   Alcoholism

6 (13.9)

35 (21.9)

0.2

   Renal impairment

3 (7.0)

10 (6.2)

0.8

   Liver disease

1 (2.3)

1 (0.6)

0.3

Prior treatment

19 (44.2)

92 (57.5)

0.08

Prior antibiotic

5 (11.6)

7 (4.4)

0.08

Clinical data

   

   Chest pain

24 (55.8)

106 (66.2)

0.1

   Hemoptysis

10 (23.2)

23 (14.4)

0.1

   Severity criteria

5 (11.6)

8 (5.0)

0.1

Laboratory results

   

Leucocytes, median 109/L (IQR)

8.5 (6.7 - 10.8)

8.3 (6.2 - 10.6)

0.6

   AST*, median U/L (IQR)

29 (25-42)

27.5 (21-38)

0.1

   ALT*, median U/L (IQR)

30 (21-32)

26 (20-34)

0.4

   Blood creatinine μmol/L (IQR)

88.4 (77.8 - 108.7)

88.4 (76.0 - 99.0)

0.6

  1. NOTE. Liver enzymes: AST (Aspartate transaminase) and ALT (Alanine transaminase)