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Table 3 Incidence rates, IR (per 1 person-year), incidence rates ratios, IRR, of risk of treatment modification due to different types of toxicities

From: Impact of gender on response to highly active antiretroviral therapy in HIV-1 infected patients: a nationwide population-based cohort study

Incidence rates and incidence rate ratios for changes in HAART during the first year due to the following reasons: Women IR 95%(CI) Men IR 95%(CI) Women vs. men (ref) unadjusted IRR 95%(CI) Women vs. men (ref) adjusted IRR 95%(CI)
Toxicity, hypersensitivity 0.09 (0.06-0.15) 0.06 (0.03-0.14) 1.43 (0.58-3.52) 1
Toxicity, gastrointestinal 0.22 (0.16-0.15) 0.16 (0.10-0.26) 1.37 (0.80-2.36) 0.97 (0.49-1.93)
Toxicity, neurological 0.19 (0.13-0.27) 0.20 (0.13-0.30) 0.96 (0.56-1.64) 1.48 (0.65-3.38)
Toxicity, other 0.18 (0.13-0.25) 0.29 (0.21-0.40) 0.62 (0.39-1.00) 1
  1. 1 No estimate available, due to shortage of events.
  2. Poisson regression analyses of incidence rates, IR (95% CI), and incidence rates ratios, IRR (95% CI), adjusted by time-updated age, race, time-updated CD4 count, time-updated viral load, prior or current AIDS at HAART initiation, body weight and initiation period (< January 1st 2003 and >= January 1st 2003).