Variables
|
Patients who survived (n = 317)
|
Patients who died (n = 77)
|
Pvalue
|
ORuadj (95% CI)
|
ORadj (95% CI)
|
---|
Age, median years (IQR)
|
24.8 (22.9-28.3)
|
23.9 (21.7-28.3)
|
0.10
|
0.95 (0.90-1.01)
| |
BMI, median (IQR)
|
25.99 (23.20-29.26)
|
27.37 (24.87-30.33)
|
0.02
|
1.10 (1.01-1.17)
|
1.26 (1.09-1.47)
|
Gestational age, median (IQR)
|
32 (26-37)
|
32 (26-38)
|
0.86
|
0.97 (0.97-1.03)
|
0.94 (0.86-1.03)
|
Comorbidity **(%)
|
25/317 (7.9)
|
6/77 (7.8)
|
0.97
|
0.98 (0.39-2.50)
| |
Pneumonia (%)
|
275/311 (88.4)
|
75/77 (97.4)
|
0.03
|
4.91 (1.16-20.86)
|
0.68(0.02-2.39)
|
Symptoms and Lab findings
| | | | | |
PaO2/FiO2, median (IQR)
| | | | | |
PaO2/FiO2 ≥ 300 (%)
|
62/164 (37.8)
|
1/55 (1.8)
| |
Referent
|
Referent
|
PaO2/FiO2 201 to 300 (%)
|
23/164 (14.0)
|
2/55 (3.6)
|
0.18
|
5.39 (0.47-62.33)
|
2.05 (0.09-46.80)
|
PaO2/FiO2 ≤ 200 (%)
|
79/164 (48.2)
|
52/55 (94.5)
|
< 0.001
|
40.81 (5.49-303.51)
|
27.16 (2.64-279.70)
|
APACHE II score, median (IQR)
|
6 (3-10)
|
12 (8-16)
|
< 0.001
|
1.13 (1.09-1.18)
|
1.07 (0.98-1.18)
|
Dyspnoea (%)
|
139/315 (44.1)
|
58/76 (76.3)
|
< 0.001
|
4.08 (2.30-7.24)
|
1.81 (0.47-7.05)
|
Hemoptysis (%)
|
33/315 (10.5)
|
21/75 (28.0)
|
< 0.001
|
3.32 (1.79-6.18)
|
1.64 (0.37-7.27)
|
CNS symptom (%)
|
29/314 (9.2)
|
19/76 (25.0)
|
< 0.001
|
3.27 (1.71-6.24)
|
2.99 (0.63-14.14)
|
AST (u/L), median (IQR)
|
35 (23-65)
|
96.10 (44.50-159.5)
|
< 0.001
|
1.007 (1.004-1.011)
|
1.00 (0.99-1.00)
|
- OR, Odds Ratio; CI, confidence Interval; ORuadj, unadjusted odds ratio; ORadj, Adjusted odds ratio; BMI, body mass index; IQR, interquartile range; APACHE II, acute physiology and chronic health evaluation II
- * Data are presented as no./total no., if otherwise stated. Percentages are based on women with complete information in the respective categories
- Variables included in univariate model: Age, BMI, Gestational age, comorbidity, pneumonia and symptoms and lab findings on admission associated with mortality
- Variables included in multivariate model: BMI, Gestational age, PaO2/FiO2 on admission, APACHE II score, dyspnoea, hemoptysis, CNS symptom, AST
- ** Comorbidity included Respiratory diseases (asthma, COPD, active tuberculosis and other bronchial disease), cardiovascular diseases (heart disease, chronic congestive heart failure, valvular disease), diabetes mellitus, cancer or hematological diseases and Immune suppressed