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Table 1 Clinical characteristics of study participants

From: HIV-1 infection is associated with changes in nuclear receptor transcriptome, pro-inflammatory and lipid profile of monocytes

Subjects

HEALTY (n=8)

HIV POSITIVE (n=8)

HAART (n=8)

P

Sex (Male/Female)

4/4

6/2

6/2

-

Age (years)

45.2 ± 4.5

47.1 ± 4.6

44.8 ± 4.4

-

BMI

24.15 ± 1.29

23.35 ± 0.99

23.37 ± 0.65

-

White Blood Cells (cells/mm3)

6347 ± 685

4756 ± 1214

5740 ± 567

-

CD4+ (cells/ml)

N/A

396.6 ± 121

851.1 ± 78 #

# < 0.05

Cholesterol (mg/dl)

201.3 ± 7.7

133.5 ± 13.8 *

226.3 ± 13.4 #

* < 0.05# < 0.05

HDL (mg/dl)

59.1 ± 5.9

28 ± 3.8 *

45.5 ± 5.9 #

* < 0.05# < 0.05

Triglycerides (mg/dl)

86.1 ± 11.6

169.7 ± 50.1

181.6 ± 29

-

Viral Load (copies/ml)

N/A

840000±552000

< 50 #

* < 0.05# < 0.05

Therapy

none

none

PI (n=5) and NNRTI (n=3)

-

Blood pressure medications

2

3

2

-

  1. *P<0.05 versus healthy donors, #P<0.05 versus HIV patients.
  2. PI, protease inhibitor; NNRT, non-nucleoside reverse transcriptase inhibitor.
  3. N/A, not applicable.