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Table 2 Review of acute osteomyelitis cases caused by CA-MRSA in adults

From: Acute haematogenous community-acquired methicillin-resistant Staphylococcus aureus osteomyelitis in an adult: Case report and review of literature

No Ref Age/ sex Underlying disease Probable source of entry Symptoms Manifestation Culture source PVL Treatment Outcome
1 11* 27/M None History of furunculosis Contact with gym facilities Leg pain and fever Femur osteomyelitis Bone + Vancomycin −8 weeks Surgical debridement Recovered and no relapse during follow-up
2 11 * 37/M Hepatitis C Hypertension History of furunculosis Contact with children with ‘skin bumps’ Leg pain and fever Femur osteomyelitis Bone + Vancomycin- 8 weeks Surgical debridement Recovered and no relapse during follow-up
IVDU
3 12 45/M None NA Right hemithorax pain and swelling Fever First rib osteomyelitis, pyomyositis, thoracic wall abscesses, septicaemia Bone, blood, pus and tissue + Clindamycin, tobramycin+ linezolide, vancomycin (given at different times for 6 weeks) Recovered
Surgical debridements Abscess drainage
4 13 * 34/M None Axillary furuncle Thigh pain Femur osteomyelitis, bacteraemia Bone and blood NA Vancomycin +rifampicin Recovered and no relapse during follow-up
– 12 weeks
Surgical debridement Intramedullary rod
5 14 * 46/F Hypertension History of furunculosis in patient and daughter Arm pain Humerus osteomyelitis with pathological fracture Bone NA Vancomycin+ rifampicin (various combination total of 16 weeks) Recovered and no relapse during follow-up
Surgical debridement
ORIF
6 14 28/F Hepatitis C History of furunculosis Subcutaneous heroin injection Thigh pain and swelling Femur osteomyelitis, pyomyositis, and bacteraemia Bone and blood NA Vancomycin, linezolide, daptomycin (various combination) Recovered and no relapse during follow-up
ORIF
Surgical debridement
7 15 22/M None Elbow cellulitis Works at military base Knee and thigh pain Fever Femur osteomyelitis. septic arthritis of knee bacteraemia, thigh abscess, endocarditis, septic lung emboli, deep vein thrombosis Wound and blood + Vancomycin + clindamycin, Survived with disabilities
Vancomycin + linezolid (various combination- total of 8 weeks)
Incision and drainage
8 16 46/M Hepatitis C with cirrhosis IVDU Back pain and fever Lumbar osteomyelitis, pyomyositis of paraspinal and psoas muscle, spinal epidural abscess, bacteraemia Blood and pus NA Abscess drainage Recovered and no relapse during follow-up
Surgical debridement Vancomycin- 6 weeks
9 Present* 28/M None Extensive direct contact with deer Thigh pain and swelling Fever Femur osteomyelitis, septic arthritis of knee pyomyositis bacteraemia Bone, blood, pus and tissue + Abscess drainage Arthrotomy Recovered and no relapse during follow-up
Case  
  Surgical debridement Vancomycin+fusidic Fusidic + rifampicin- 6 months
     Consumed deer meet       
  1. *Suspected primary bone malignancy.
  2. NA- not available.