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Table 2 Characteristics of 130 patients with VAP with regard to the adequacy of empirical antibiotic treatment

From: Inadequate treatment of ventilator-associated and hospital-acquired pneumonia: Risk factors and impact on outcomes

Characteristics Adequate treatment n = 44 Inadequate treatment n = 86 p
Age (years) 65.64 ± 16.42 64.15 ± 16.83 0.628
Sex (male) 29 (65.9) 48 (55.8) 0.358
Surgical unit 22 (45.8) 26 (54.2) 0.044
Underlying diseases    
 Diabetes mellitus 6 (13.6) 13 (15.1) 1.000
 COPD 15(34.1) 18 (20.9) 0.156
 Chronic renal failure 1 (2.3) 4 (4.7) 0.672
 Congestive heart failure 7 (15.9) 15 (17.4) 1.000
 Cerebrovascular disease 5 (11.4) 16 (18.6) 0.418
 Malignancy 6 (13.6) 13 (15.1) 1.000
Central venous catheterization 34 (77.3) 62 (72.1) 0.671
Urinary catheterization 43 (97.7) 84 (97.7) 1.000
Late-onset VAP 36 ( 81.8) 75 (87.2) 0.575
Presence of other site infection 12 (27.3) 42 (48.8) 0.030
Previous antibiotic usage 12 (27.3) 39 (45.3) 0.071
Culture proven pneumonia 37 (84.1) 80 (93.0) 0.128
Polymicrobial etiology 2 (4.5) 6 (7.0) 0.186
MDR bacteria 32 (72.7) 60 (69.8) 0.883
Length of stay before VAP 12.61 ± 11.20 14.31 ± 10.348 0.138
APACHE II score 16.39 ± 6.71 16.81 ± 6.63 0.730