Table 2 Characteristics of 130 patients with VAP with regard to the adequacy of empirical antibiotic treatment
Characteristics | Adequate treatment n = 44 | Inadequate treatment n = 86 | p |
|---|---|---|---|
Age (years) | 65.64 ± 16.42 | 64.15 ± 16.83 | 0.628 |
Sex (male) | 29 (65.9) | 48 (55.8) | 0.358 |
Surgical unit | 22 (45.8) | 26 (54.2) | 0.044 |
Underlying diseases | |||
Diabetes mellitus | 6 (13.6) | 13 (15.1) | 1.000 |
COPD | 15(34.1) | 18 (20.9) | 0.156 |
Chronic renal failure | 1 (2.3) | 4 (4.7) | 0.672 |
Congestive heart failure | 7 (15.9) | 15 (17.4) | 1.000 |
Cerebrovascular disease | 5 (11.4) | 16 (18.6) | 0.418 |
Malignancy | 6 (13.6) | 13 (15.1) | 1.000 |
Central venous catheterization | 34 (77.3) | 62 (72.1) | 0.671 |
Urinary catheterization | 43 (97.7) | 84 (97.7) | 1.000 |
Late-onset VAP | 36 ( 81.8) | 75 (87.2) | 0.575 |
Presence of other site infection | 12 (27.3) | 42 (48.8) | 0.030 |
Previous antibiotic usage | 12 (27.3) | 39 (45.3) | 0.071 |
Culture proven pneumonia | 37 (84.1) | 80 (93.0) | 0.128 |
Polymicrobial etiology | 2 (4.5) | 6 (7.0) | 0.186 |
MDR bacteria | 32 (72.7) | 60 (69.8) | 0.883 |
Length of stay before VAP | 12.61 ± 11.20 | 14.31 ± 10.348 | 0.138 |
APACHE II score | 16.39 ± 6.71 | 16.81 ± 6.63 | 0.730 |