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Table 4 Multivariable analysis for predictors of qRT-PCR confirmed influenza infection and clinical influenza among included households in separate models allowing for within household correlation.

From: The role of facemasks and hand hygiene in the prevention of influenza transmission in households: results from a cluster randomised trial; Berlin, Germany, 2009-2011

 

Variable

RT-PCR confirmed Influenza

ILI

  

OR

95% CI

p-value

OR

95% CI

p-value

Complete

Data

Intervention Group*

      
 

   Control Group

Ref.

  

Ref.

  
 

   Mask Group

0.39

0.13-1.17

0.09

0.61

0.2-1.87

0.39

 

   Mask & Hygiene Group

0.62

0.23-1.65

0.34

0.50

0.16-1.58

0.24

 

Intervention Groups combined*

      
 

   Control Group

Ref.

  

Ref.

  
 

Mask Group +

Mask & Hygiene Group

0.50

0.21-1.19

0.12

0.55

0.22-1.40

0.21

2009/2010

Intervention Group*

      
 

   Control Group

Ref.

  

Ref.

  
 

   Mask Group

0.34

0.07-1.76

0.20

0.74

0.17-3.2

0.68

 

   Mask & Hygiene Group

0.23

0.05-1.13

0.07

0.41

0.09-1.84

0.24

 

Intervention Groups combined*

      
 

   Control Group

Ref.

  

Ref.

  
 

Mask Group +

Mask & Hygiene Group

0.28

0.08-1.05

0.06

0.54

0.16-1.85

0.32

2010/2011

Intervention Group*

      
 

   Control Group

Ref.

  

Ref.

  
 

   Mask Group

0.35

0.07-1.63

0.18

0.37

0.06-2.35

0.3

 

   Mask & Hygiene Group

1.0

0.26-3.78

1.0

0.55

0.09-3.44

0.5

 

Intervention Groups combined*

      
 

   Control Group

Ref.

  

Ref.

  
 

   Mask & Hygiene Group

0.63

0.19-2.11

0.45

0.45***

0.1-2.0

0.3

Implementation

of intervention

< 36 h after

symptom onset

Intervention Group**

      
 

   Control Group

Ref.

  

Ref.

  
 

   Mask Group

0.21

0.02-2.02

0.18

0.63

0.08-4.92

0.66

 

   Mask & Hygiene Group

0.13

0.01-1.28

0.08

0.17

0.01-2.03

0.16

 

Intervention Groups combined**

      
 

   Control Group

Ref.

  

Ref.

  
 

Mask Group +

Mask & Hygiene Group

0.16

0.03-0.92

0.04

0.34

0.06-2.13

0.25

Only A/H1N1 pdm09 Infection

Intervention Group*

      
 

   Control Group

Ref.

  

Ref.

  
 

   Mask Group

0.37

0.12-1.19

0.10

0.55

0.17-1.84

0.33

 

   Mask & Hygiene Group

0.27

0.07-0.99

0.049

0.26

0.06-1.15

0.08

 

Intervention Groups combined*

      
 

   Control Group

Ref.

  

Ref.

  
 

Mask Group +

Mask & Hygiene Group

0.33

0.12-0.88

0.027

0.41

0.14-1.19

0.1

  1. Intention-to-treat analysis. (n = 216 household contacts)
  2. OR Odds ratio, 95% CI 95% Confidence Interval. * adjusted for age, sex, timely therapy of the index, vaccination of household contacts, time spent at home. ** adjusted for age, sex, timely therapy of the index, time spent at home. *** adjusted for age and sex
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BMC Infectious Diseases

ISSN: 1471-2334

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