Base case
|
219
|
450
|
Cost per year of life saved (no quality of life adjustments)
|
253
|
503
|
HPV16/18-related cervical diseases only
|
448
|
698
|
Duration of vaccine protection = 20 years
|
Dominated1
|
656
|
Vaccine coverage= 50% for routine and 60% for catch-up
|
106
|
250
|
Vaccine coverage= 95% for routine and 98% for catch-up
|
258
|
425
|
High cost of vaccine series (increased by 25%)
|
406
|
686
|
High cost of treating HPV-related disease (increased by 25%)
|
86
|
326
|
Low cost of treating HPV-related disease (decreased by 25%)
|
350
|
573
|
Discounted at 0%
|
Cost saving
|
Cost saving
|
Discounted at 5%
|
900
|
1201
|
Pessimistic scenario2
|
Dominated1
|
998
|