| |
AUC (95% CI)
|
Cut-off
|
Sensitivity (%)
|
Specificity (%)
|
PPV (%)
|
NPV (%)
|
LR(+)
|
LR(−)
|
Accuracy (%)
|
|---|
|
PCT D0 [ng/ml]
|
0.990 (0.972 – 1.000)
|
>0.70
|
92.3 (73.4 – 98.7)
|
100 (80.0 – 100)
|
100.0
|
90.9
|
n.a.
|
0.08
|
95.7
|
|
ΔPCTD-1, D0 [ng/ml]
|
0.982 (0.941 – 1.000)
|
>0.20
|
100 (84.0 – 100)
|
95.0 (73.1 – 99.7)
|
96.3
|
100.0
|
20.0
|
0.0
|
97.8
|
|
ΔPCTD-2, D0 [ng/ml]
|
0.992 (0.975 – 1.000)
|
>0.20
|
100 (84.0 – 100)
|
95.0 (73.1 – 99.7)
|
96.3
|
100.0
|
20.0
|
0.0
|
97.8
|
|
ΔPCTD-3, D0 [ng/ml]
|
0.980 (0.939 – 1.000)
|
>0.20
|
96.2 (78.4 – 99.8)
|
95.0 (73.1 – 99.8)
|
96.2
|
95.0
|
19.2
|
0.04
|
95.6
|
|
ΔPCTD-4, D0 [ng/ml]
|
0.982 (0.946 – 1.000)
|
>0.20
|
96.2 (78.4 – 99.8)
|
95.0 (73.1 – 99.8)
|
96.2
|
95.0
|
19.2
|
0.04
|
95.6
|
|
WBC D0 [10 3/μl]
|
0.539 (0.369 – 0.709)
|
>15.64
|
57.7 (37.2 – 76.0)
|
60.0 (36.4 – 80.0)
|
65.2
|
52.2
|
1.44
|
0.71
|
58.7
|
|
CRP D0 [mg/dl]
|
0.603 (0.438 – 0.768)
|
>16.90
|
50.0 (30.4 – 69.6)
|
70.0 (45.7 – 87.2)
|
68.4
|
51.9
|
1.67
|
0.71
|
58.7
|
- AUC (95% confidence interval, CI), positive (PPV) and negative (NPV) predictive value, LR(+) likelihood ratio positive, and LR(−) likelihood ratio negative.
