In-vitroanalysis of the microbicidal activity of 6 contact lens care solutions

BMC Infectious Diseases

Table 5 Proportions of reduction factors exceeding pre-specified thresholds for each CL care solution and for each tested microorganism / without organic load

	S. aureus				P. aeruginosa				S. marcescens				C. albicans				F. solani
	RF ≥ 3		RF ≥ 5		RF ≥ 3		RF ≥ 5		RF ≥ 3		RF ≥ 5		RF ≥ 1		RF ≥ 4		RF ≥ 1		RF ≥ 4
	%	N	%	N	%	N	%	N	%	N	%	N	%	N	%	N	%	N	%	N
AOSEPT PLUS	100	6	100	6	100	6	100	6	100	6	100	6	100	6	100	6	100	6	100	6
BlueVision	0	6	0	6	100	6	100	6	100	6	100	6	100	6	100	6	100	6	100	6
Easy Sept	0	6	0	6	100	6	100	6	100	6	100	6	100	6	100	6	100	6	100	6
Oxysept Comfort	0	6	0	6	100	6	100	6	100	6	100	6	100	6	100	6	100	6	100	6
Optifree Replenish	0	6	0	6	91.7	12	75	12	91.7	12	8.3	12	100	12	25	12	100	12	91.7	12
Solocare Aqua	0	6	0	6	0	6	0	6	0	6	0	6	91.7	12	33.3	12	100	12	58.3	12
χ ² test	< 0.001		< 0.001		< 0.001		< 0.001		< 0.001		< 0.001		0.690		< 0.001		1		0.024

The intervals ≥ 3.0 log [CFU/ml] for bacteria and ≥ 1.0 log [CFU/ml] for fungi were assessed according to the criteria of the EN ISO 14729 Stand Alone Test [47]. The intervals ≥ 5.0 log [CFU/ml] for bacteria according to the criteria of the norms EN 1040 [58], EN 13727 [59] and EN 1276 [60] and ≥ 4.0 log [CFU/ml] for fungi according to the criteria of the norms EN 1275 [61], EN 13624 [62] and EN 1650 [63] were assessed.

ISSN: 1471-2334